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How it works?

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We have a selection of treatments available for various conditions.

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Before ordering this treatment, you may have to complete an online consultation

Overview

When acne feels stubborn and keeps coming back, Aknemycin Plus offers a dual-action approach. Combining an antibiotic (erythromycin) to fight acne-causing bacteria with a retinoid (tretinoin) to unclog pores, it tackles both the cause and the effect of breakouts.

Applied directly to problem areas, Aknemycin Plus works to reduce inflammation, clear existing spots, and prevent new ones from forming. With consistent use, it helps restore clearer skin and rebuild confidence.

This medicine requires a secure online consultation with a UK-registered prescriber, and will only be supplied if clinically appropriate.


What is Aknemycin Plus 


Aknemycin Plus is a prescription-only topical treatment designed for acne. It combines two active ingredients that work in different but complementary ways. Erythromycin, an antibiotic, targets the acne-causing bacteria to help reduce inflammation, while tretinoin, a retinoid, encourages healthy skin cell turnover and helps keep pores clear. By addressing both the bacterial and skin cell causes of breakouts, Aknemycin Plus offers an effective option for mild to moderate inflammatory acne, particularly in cases where single treatments alone have not provided sufficient results.

Directions

  • Apply a thin layer to affected areas once or twice daily, as directed by your prescriber.
  • Wash and gently dry your skin before application.
  • Avoid contact with eyes, mouth, nostrils, and broken skin.
  • Consistency is key — noticeable improvement is usually seen after 6–8 weeks.
  • Always use sunscreen during the day, as tretinoin can make skin more sensitive to sunlight.

Side Effects

Like all medicines, Aknemycin Plus can cause side effects, although not everyone will experience them.

Common (may affect up to 1 in 10 people):

  • Temporary redness
  • Dryness or peeling
  • Mild burning or irritation


Less common (may affect up to 1 in 100 people):

  • Skin sensitivity to sunlight
  • Increased risk of irritation when used with harsh skincare products


Most people tolerate Aknemycin Plus well, and side effects (if they do occur) are usually mild. If you are concerned about any symptoms, or they do not improve, speak to your doctor, pharmacist, or prescriber.

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet provided with your medicine for full details. If you experience severe or worrying symptoms, seek medical advice straight away. In an emergency, call 999 or go to A&E.

Warnings

Aknemycin Plus may not be suitable if you:

  • Are pregnant or breastfeeding (tretinoin is not recommended)
  • Have very sensitive or eczema-prone skin
  • Are already using other topical retinoids or antibiotics (risk of irritation/resistance)


Always avoid excessive sun exposure and use a broad-spectrum SPF while on treatment.

FAQ's

How does Aknemycin Plus work?
It combines erythromycin (antibiotic) and tretinoin (retinoid) to fight bacteria, reduce inflammation, and keep pores clear.

How long before I see results?
Most people see improvements within 6–8 weeks of consistent use.

Can I use Aknemycin Plus with other acne creams?
Only under prescriber advice. Using multiple retinoids or antibiotics together may increase irritation or reduce effectiveness.

Does it cure acne permanently?
No — acne may return once treatment is stopped, but many people achieve long-term improvement with consistent use.

Can teenagers use Aknemycin Plus?
Yes — it is often prescribed for teenagers with persistent acne, but only after consultation with a healthcare professional.