Images for illustrative purposes only

How it works?

Online Consultation

We ask you to complete a quick and easy consultation and get you started.

Choose condition

We have a selection of treatments available for various conditions.

Express Delivery

You will have complete visibility and control of your delivery.
Notice!

Before ordering this treatment, you may have to complete an online consultation

Overview

When ordinary heartburn remedies just don’t go far enough, Nexium offers trusted, long-lasting relief. Known as the “purple pill” worldwide, Nexium contains esomeprazole — a next-generation proton pump inhibitor (PPI) designed to calm excess stomach acid and protect against reflux, indigestion, and ulcers. With its proven track record and powerful protection, Nexium helps you enjoy meals, rest peacefully, and get on with your day without the burn of acid reflux holding you back.

At SwiftMedi, your suitability for Nexium will always be reviewed by a UK-registered prescriber following a secure online consultation, with discreet delivery direct to your door.

What is Nexium


Nexium is the branded version of esomeprazole, one of the most widely prescribed proton pump inhibitors (PPIs). It works by blocking the acid-producing pumps in the stomach lining, providing powerful and long-lasting relief from reflux and related conditions.

Nexium is prescribed for heartburn and acid reflux, gastro-oesophageal reflux disease (GORD), and for the healing and prevention of stomach or duodenal ulcers. It is also used to reduce the risk of ulcers in patients taking NSAIDs long-term, and to manage conditions involving excess stomach acid such as Zollinger–Ellison syndrome.

Trusted by millions of patients worldwide, Nexium is often chosen as a premium branded option, offering dependable relief for those seeking proven, effective control of reflux symptoms.

Directions

  • Usual adult dose: 20mg to 40mg once daily, depending on the condition.
  • Take in the morning, preferably before eating.
  • Swallow tablets whole with water — do not chew or crush.
  • Short-term use: typically 2–4 weeks for symptom relief.
  • Longer courses may be prescribed for GORD or ulcer prevention.


Always follow your prescriber’s advice.

Side Effects

Like all medicines, Nexium (esomeprazole) can cause side effects, although not everyone will experience them. Most are mild, short-lived, and improve as your body adjusts to treatment.

Common (may affect up to 1 in 10 people):

  • Headache – usually mild and temporary.
  • Stomach pain, diarrhoea, constipation, or nausea – digestive problems are the most common effects but are generally mild.
  • Wind (flatulence) – some patients may experience bloating or excess gas.


Uncommon (may affect up to 1 in 100 people):

  • Dizziness, tiredness, or sleep problems – may affect alertness; avoid driving if you feel unwell.
  • Skin rash or itching – usually mild, but seek advice if persistent.
  • Dry mouth or altered taste – generally temporary.


Rare but serious (seek urgent medical advice):

  • Severe allergic reaction (anaphylaxis) – symptoms include swelling of the lips, face, tongue, or throat, difficulty breathing, or a sudden rash.
  • Severe abdominal pain or vomiting blood – may indicate stomach bleeding or ulcer complications.
  • Yellowing of the skin or eyes (jaundice) – could be a sign of liver problems.


Most people tolerate Nexium well, and side effects (if they occur) are usually mild. If you are worried about any symptoms, or if they do not improve, speak to your doctor, pharmacist, or prescriber.

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet provided with your medicine for full details. If you experience severe or worrying symptoms, seek medical advice straight away. In an emergency, call 999 or go to A&E.

Warnings

Nexium may not be suitable if you:

  • Are allergic to esomeprazole, omeprazole, or other PPIs
  • Have liver problems
  • Take medicines such as warfarin, clopidogrel, methotrexate, or digoxin
  • Are pregnant or breastfeeding — consult your doctor first
  • Require long-term treatment — your prescriber may recommend monitoring vitamin B12, magnesium, or bone health
Frequently asked questions

  • Is Nexium better than Omeprazole?

    Some patients find Nexium provides longer-lasting or more reliable relief compared to standard omeprazole

  • How fast does Nexium work?

    Relief usually begins within a few days, but full benefit may take 1–2 weeks.

  • How should I take Nexium?

    Take once daily in the morning, before food, with water.

  • Can I take Nexium long-term?

    Yes, under medical supervision. Regular check-ups may be recommended.

  • Does Nexium cure reflux?

    It controls acid production and allows healing but may need to be combined with lifestyle changes for lasting results.

  • Can I drink alcohol while taking Nexium?

    Yes, but alcohol can worsen reflux symptoms.