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Overview

Heartburn and acid reflux can creep into every part of life — making meals uncomfortable, nights restless, and daily routines frustrating. Omeprazole is one of the UK’s most trusted treatments for reflux and indigestion, working by calming excess stomach acid at its source. By easing burning pain, protecting your oesophagus, and helping your body heal, Omeprazole gives you the freedom to eat, sleep, and live with confidence again.

At SwiftMedi, every request for Omeprazole is carefully reviewed by a UK-registered prescriber through a secure online consultation, with discreet delivery direct to your door.


What is Omeprazole


Omeprazole is a medicine from the group known as proton pump inhibitors (PPIs). It works by blocking the acid-producing pumps in the stomach, which lowers the amount of acid made and helps prevent further irritation to the oesophagus and stomach lining.

It is commonly prescribed for frequent heartburn and acid reflux, gastro-oesophageal reflux disease (GORD), and for the treatment of stomach or duodenal ulcers. Omeprazole is also used as protection against ulcers in patients who need to take NSAIDs long-term.

With decades of safe and effective use, omeprazole is often the first-line choice for reflux and related conditions, providing reliable, long-lasting relief and helping patients return to everyday comfort.

Directions

  • Usual adult dose: 10mg to 40mg once daily, depending on severity and condition.
  • Take in the morning, preferably before food.
  • Swallow capsules whole with water — do not crush or chew.
  • Some patients may need a short course (2–4 weeks), while others may require longer-term treatment for GORD.
  • Always follow the instructions provided by your prescriber.

Side Effects

Like all medicines, omeprazole can cause side effects, although not everyone will experience them. Most are mild and improve as your body adjusts to treatment.

Common (may affect up to 1 in 10 people):

  • Headache – usually mild and short-lived.
  • Stomach pain, diarrhoea, constipation, or nausea – digestive symptoms are the most common effects but are generally mild.
  • Wind (flatulence) – some people may experience bloating or excess gas.


Uncommon (may affect up to 1 in 100 people):

  • Dizziness, tiredness, or sleep disturbances – these may affect alertness; avoid driving if you feel unwell.
  • Dry mouth or changes in taste – usually mild and temporary.
  • Skin rash or itching – typically mild but seek advice if persistent.


Rare but serious (seek urgent medical advice):

  • Severe allergic reaction (anaphylaxis) – symptoms include swelling of the face, lips, tongue, or throat, difficulty breathing, or a sudden rash.
  • Severe abdominal pain or vomiting blood – may indicate stomach bleeding or ulcer complications.
  • Yellowing of the skin or eyes (jaundice) – a possible sign of liver problems.


Most people tolerate omeprazole well, and side effects are usually mild. If you are concerned about any symptoms, or if they do not improve, speak to your doctor, pharmacist, or prescriber.

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet provided with your medicine for full details. If you experience severe or worrying symptoms, seek medical advice straight away. In an emergency, call 999 or go to A&E.

Warnings

Omeprazole may not be suitable if you:

  • Are allergic to omeprazole, esomeprazole, or other PPIs
  • Have liver disease
  • Are taking medicines such as warfarin, phenytoin, clopidogrel, methotrexate, or HIV treatments
  • Are pregnant or breastfeeding — seek medical advice first
  • Need long-term use — monitoring may be required for vitamin B12, magnesium levels, or bone health

FAQ's

How quickly does Omeprazole work?
Most people notice improvement within a few days, with maximum benefit after 1–2 weeks.

Can I take Omeprazole with food?
Yes, but it works best when taken before meals.

Is Omeprazole safe for long-term use?
It can be used long-term under medical supervision, but regular check-ups are recommended.

What’s the difference between Omeprazole and Esomeprazole?
Both are PPIs; esomeprazole may last longer in the body for some patients, but many respond equally well to omeprazole.

Can I drink alcohol with Omeprazole?
Alcohol doesn’t affect how it works, but may worsen reflux symptoms.

Does Omeprazole cure reflux?
It controls acid and allows healing, but lifestyle changes may also be needed to prevent recurrence.