Differin Gel contains adapalene, a retinoid that helps unclog pores, reduce inflammation and prevent new breakouts forming. The gel base absorbs quickly and is often preferred for oilier skin types. It is commonly used when standard acne products have not been effective.

Differin Gel is usually slightly more potent than the cream because it penetrates oily or congested skin more easily. This makes it helpful for blackheads and pore blockage, but it may cause more dryness in sensitive skin. A clinician can help decide which formulation suits you best.

Differin Gel often begins to show improvement after four to six weeks, but full results may take up to three months. Some people notice early irritation or a temporary flare in breakouts as their skin adjusts. Consistent use gives the best long-term results.

Apply a small amount once daily at night to clean, dry skin, avoiding the eyes and mouth. A thin layer is enough; using more can increase irritation without speeding results. Allow it to fully absorb before applying moisturiser.

Common effects include dryness, redness, mild peeling or stinging, especially in the first few weeks. These usually settle as your skin adjusts. If irritation becomes severe, reducing frequency or adjusting your skincare routine may help.

Differin Gel is not recommended if you are pregnant, planning pregnancy or breastfeeding. It may also be unsuitable for people with eczema or very sensitive skin. Your clinician can suggest alternatives if needed.

Yes. Differin Gel is prescription-only and available through regulated UK online pharmacies after completing a consultation. This ensures it is safe for your skin and appropriate for your acne type.

Yes. Differin Gel is often preferred for oily or combination skin because its gel base absorbs quickly and doesn’t feel heavy. It helps clear blocked pores and reduces shiny or congested areas over time. People with dry or sensitive skin may prefer the cream version instead.

Differin Gel is particularly effective for blackheads and whiteheads because adapalene keeps pores clear and prevents new blockages. Results appear gradually as skin turnover increases. With regular use, many people see fewer bumps and a smoother texture.

Differin Gel can help with mild hormonal acne by reducing pore blockage and calming inflammation. However, deeper cystic hormonal breakouts may need additional treatments like oral antibiotics or hormonal therapy. A clinician can guide the best approach.

Yes. Many people use moisturiser to reduce dryness. You can apply moisturiser after Differin Gel once it has absorbed, or apply it before as a buffer if your skin is sensitive. This helps maintain comfort while you continue treatment.

Yes. Differin Gel increases sun sensitivity, making your skin more prone to redness or irritation. Use sunscreen daily and avoid prolonged sun exposure during treatment. This helps protect your skin and prevents flare-ups.

Some people experience temporary worsening, known as purging, as Differin speeds up skin turnover and clears clogged pores. This phase usually improves within a few weeks. Consistency is key to achieving long-term benefits.

If there is little improvement after several weeks, your clinician may suggest combining Differin with benzoyl peroxide, using an antibiotic gel or considering oral treatments. Adjusting your treatment plan often leads to better results.