• Targets acne-causing bacteria to reduce infection and inflammation
  • Unclogs pores and prevents new spots from forming
  • Effective for both inflammatory and comedonal acne 

How it works?

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Before ordering this treatment, you may have to complete an online consultation

Overview

Treclin Gel brings together two proven acne-fighting ingredients in one treatment — clindamycin to kill bacteria and reduce inflammation, and tretinoin to keep pores clear and prevent new spots forming.

This combination not only works on active breakouts but also helps reduce blackheads and whiteheads, giving your skin the chance to heal and stay clearer over time. It’s often prescribed when single treatments haven’t been enough, making it a trusted next step for many acne sufferers.

This medicine requires a secure online consultation with a UK-registered prescriber, and will only be supplied if clinically appropriate.


What is Treclin Gel


Treclin Gel is a prescription topical treatment that combines two active ingredients for a comprehensive approach to acne. Clindamycin (1%), an antibiotic, works to reduce acne-causing bacteria and calm inflammation, while tretinoin (0.025%), a retinoid, helps to increase skin cell turnover, unclog pores, and prevent new breakouts from forming. This dual-action formula makes Treclin effective for both inflammatory acne (red, sore spots) and comedonal acne (blackheads and whiteheads), helping to address multiple causes of acne and break the cycle of recurring flare-ups.

Directions

  • Apply a thin layer once daily in the evening to clean, dry skin.
  • Use only on affected areas — avoid the eyes, lips, nostrils, and broken skin.
  • Wash hands after applying.
  • Expect some initial irritation — redness, dryness, or peeling are common at first and usually improve over time.
  • Always wear sunscreen during the day, as tretinoin increases sun sensitivity.


Visible improvement usually occurs within 6–8 weeks, with clearer skin continuing over several months.

Side Effects

Like all medicines, Treclin Gel can cause side effects, although not everyone will experience them.

Common (may affect up to 1 in 10 people, especially in the first few weeks):

  • Redness
  • Dryness or peeling
  • Mild burning or stinging


Less common (may affect up to 1 in 100 people):

  • Persistent irritation that does not settle
  • Increased sensitivity to sunlight


Rare (may affect up to 1 in 1,000 people):

  • Allergic reaction (stop treatment and seek medical advice if severe)


Most people tolerate Treclin Gel well, and side effects (if they do occur) are usually mild. If you are concerned about any symptoms, or they do not improve, speak to your doctor, pharmacist, or prescriber.

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet provided with your medicine for full details. If you experience severe or worrying symptoms, seek medical advice straight away. In an emergency, call 999 or go to A&E.

Warnings

Treclin may not be suitable if you:

  • Are pregnant or planning pregnancy (tretinoin must not be used)
  • Are breastfeeding (should be avoided unless specifically advised)
  • Have very sensitive or eczema-prone skin
  • Are using other strong acne treatments (such as oral retinoids)


Always avoid tanning beds and protect your skin with a broad-spectrum SPF daily.

FAQ's

How does Treclin Gel work?
It combines clindamycin (antibiotic) to fight bacteria with tretinoin (retinoid) to unclog pores and prevent new spots.

How long does Treclin take to work?
Most patients see improvements within 6–8 weeks, but optimal results may take several months.

Will my acne get worse before it gets better?
Yes, it’s common to experience an initial flare-up as tretinoin increases skin turnover — this usually settles with continued use.

Can I use Treclin with moisturisers?
Yes — using a gentle, non-comedogenic moisturiser can help manage dryness and irritation.

Is Treclin stronger than Duac?
Treclin targets clogged pores more effectively due to tretinoin, while Duac focuses more on bacterial acne — your prescriber will choose the best option for your skin.

Can teenagers use Treclin?
Yes, it is often prescribed to teenagers with moderate acne, under medical supervision.