• Dual antibiotic protection against ear infections
  • Rapid relief from pain itching and swelling
  • Trusted prescription strength ear drop treatment

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Overview

Sofradex Ear Drops provide fast relief from painful ear infections by combining antibiotic and anti-inflammatory action in one simple treatment.
They not only clear infection but also reduce itching, swelling, and discomfort - helping you feel better quickly.


What is Sofradex


Otitis externa (outer ear infection) can cause intense pain, itching, discharge, and temporary hearing loss. Sofradex targets all these symptoms at once, making it one of the most widely prescribed ear treatments in the UK.

Each drop contains:

  • Framycetin: a potent antibiotic that kills the bacteria responsible for ear infections.
  • Gramicidin: another antibiotic that boosts antibacterial coverage.
  • Dexamethasone: a corticosteroid that calms inflammation and reduces swelling.


By delivering two antibiotics plus an anti-inflammatory, Sofradex provides comprehensive relief from both infection and inflammation. Most patients start noticing improvement within a few days, with full recovery expected in 7–10 days.

Directions

  • Usually 2–3 drops into the affected ear 3–4 times daily, or as directed by your prescriber.
  • Complete the full course, even if symptoms improve earlier.
  • Avoid use for more than 7 days unless instructed by a healthcare professional.

Side Effects

Most people tolerate Sofradex well, but mild side effects may occur.

Common (may affect up to 1 in 10 people):

  • Temporary stinging or burning in the ear
  • Mild irritation or itching


Less common (may affect up to 1 in 100 people):

  • Skin rash around the ear
  • Thinning of the skin with prolonged use (due to the steroid)


Rare but serious (seek urgent medical help):

  • Severe allergic reaction (swelling, rash, difficulty breathing)
  • Worsening pain, swelling, or hearing loss


Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine for full details. If you notice anything unusual or concerning, stop using the drops and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

  • Not suitable if allergic to framycetin, gramicidin, or dexamethasone.
  • Avoid if you have a perforated eardrum, unless prescribed by a specialist.
  • Use with caution if you have long-term ear problems or skin sensitivity.
Frequently asked questions

  • What is Sofradex and how does it work?

    Sofradex contains two antibiotics, framycetin and gramicidin, which treat bacterial ear infections, plus dexamethasone to reduce inflammation and swelling. This combination helps relieve pain, itching and discharge commonly seen in otitis externa. It is only for use in the ear unless otherwise directed by a clinician.

  • How fast does Sofradex start working?

    Many people notice reduced pain and irritation within 24-48 hours of starting Sofradex, with symptoms continuing to improve over the following days. Most infections resolve within a week if the drops are used correctly. If symptoms worsen or fail to improve after 72 hours, seek further clinical advice.

  • How do I use Sofradex safely and effectively?

    Warm the bottle in your hands, tilt your head sideways and place 2–3 drops 3–4 times a day. Keep your head tilted for a few minutes to help the medication spread. Do not insert cotton buds or objects into the ear during treatment. Always complete the full course even if symptoms improve quickly.

  • Can Sofradex help with itching and swelling in the ear?

    Yes. The dexamethasone in Sofradex helps calm inflammation, which reduces itching, redness and swelling. The antibiotics simultaneously treat the underlying bacterial infection. This dual action makes Sofradex particularly helpful when the ear canal is sore, inflamed or producing discharge.

  • Can I get my ear wet while using Sofradex?

    No. You should avoid swimming, diving or getting shower water into the ear while treating an infection. Water contributes to irritation and may delay recovery. You can use a small amount of petroleum-coated cotton to protect the ear during washing if needed.

  • Can Sofradex be used for ear eczema or allergic irritation?

    Sofradex may help when eczema or allergic inflammation contributes to discomfort in the ear canal because the steroid component reduces swelling and itching. However, if irritation is caused by sensitivity to ingredients or recurrent skin conditions, a clinician may recommend alternative treatments.

  • Does Sofradex help with ear discharge or a blocked sensation?

    Yes. Sofradex often reduces discharge and blockage caused by inflammation and infection. As swelling settles, the ear may feel less full and hearing can improve. If thick discharge continues or worsens, reassessment may be required to rule out resistant infection or fungal overgrowth.

  • Can I use Sofradex in both ears at the same time?

    Yes, if prescribed for bilateral otitis externa. Infections in both ears may suggest contributing factors such as eczema, allergies or frequent water exposure. A clinician may provide additional recommendations to prevent recurrence once the flare has settled.

  • How long is it safe to use Sofradex for?

    Sofradex is typically prescribed for 7-10 days. Extended use should be avoided unless advised by a clinician because prolonged steroid exposure in the ear canal can thin the skin or mask worsening infection. Regular review helps ensure safe and effective treatment.

  • Can Sofradex affect my hearing while using it?

    Sofradex does not impact hearing when used correctly. Temporary muffled hearing may occur due to swelling or fluid in the canal, and this usually improves as the infection resolves. If hearing becomes worse or fails to improve, seek reassessment.

  • Can Sofradex be used after ear microsuction or ear cleaning?

    Yes. Sofradex is often prescribed after professional ear cleaning because the drops can reach the inflamed tissue more effectively. The ear may feel slightly sensitive immediately after the procedure, but discomfort usually settles quickly as treatment begins.

  • Can Sofradex treat fungal ear infections?

    No. Sofradex targets bacterial infections and does not treat fungal otitis externa. If itching becomes severe, symptoms worsen or discharge takes on a fluffy or coloured appearance, a clinician may check for fungal infection and prescribe the appropriate antifungal drops.

  • What should I do if Sofradex causes burning or irritation?

    Mild stinging can occur with the first few doses, especially if the ear canal is inflamed. Persistent burning, increased redness or worsening pain may indicate irritation or sensitivity. Stop using the drops and seek advice if symptoms continue, as a switch to a different treatment may be needed.

  • Can I wear hearing aids or earphones while using Sofradex?

    It’s best to avoid earphones, earbuds and hearing aids while the ear is inflamed because they trap heat and moisture, increasing irritation. Once the condition improves and the ear canal is comfortable, you can gradually resume normal use.

  • What should I do if Sofradex isn’t improving my symptoms?

    If symptoms do not begin to improve within 48-72 hours, or if pain and discharge worsen, a clinician may reassess the infection. Causes may include resistant bacteria, fungal overgrowth or severe swelling. An alternative preparation or ear cleaning may be advised.

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