• Provides fast relief from sneezing and a runny nose
  • Offers 24-hour control of severe allergy symptoms
  • Combines two proven treatments for stronger relief

How it works?

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Overview

When hayfever symptoms are at their worst, a single treatment isn’t always enough. Dymista combines the power of an antihistamine and a corticosteroid in one nasal spray — providing rapid, targeted relief from sneezing, congestion, itchy nose, and runny nose. Fast-acting and long-lasting, it helps control even the toughest allergy symptoms so you can breathe freely and feel like yourself again.

This medicine requires a secure online consultation with a UK-registered prescriber, and will only be supplied if clinically appropriate.


What is Dymista 


Dymista is a prescription-only nasal spray that combines two proven allergy treatments in one: azelastine hydrochloride, an antihistamine, and fluticasone propionate, a corticosteroid. This unique dual-action formula tackles symptoms in two ways — azelastine blocks histamine to reduce sneezing, itching, and a runny nose, while fluticasone eases inflammation and swelling in the nasal passages to relieve congestion.

It is commonly prescribed for severe hay fever (seasonal allergic rhinitis) as well as year-round nasal allergies (perennial rhinitis).

With relief beginning within minutes of use, Dymista offers powerful 24-hour control of nasal allergy symptoms, including sneezing, congestion, and runny nose. It may also help to reduce itchy, watery eyes often linked to hay fever, providing complete and convenient allergy management in a single spray.

Directions

  • Adults (18+): One spray into each nostril twice daily (morning and evening)
  • Shake bottle before use
  • Use regularly for best results — especially during pollen season
  • Relief may be noticeable within 15–30 minutes, with full benefit in a few days

 

Side Effects

Like all medicines, Dymista can cause side effects, although not everyone will experience them. Most are mild, short-lived, and improve as your body adjusts to treatment.

Common (may affect up to 1 in 10 people):

  • Bitter taste in the mouth – this can occur after use. Tilting your head forward slightly when spraying may help reduce this.
  • Nosebleeds – generally mild and short-lasting.
  • Nasal irritation or discomfort – some people may notice stinging, burning, or dryness inside the nose, which usually settles with continued use.


Less common (may affect up to 1 in 100 people):

  • Headache – typically mild and temporary.
  • Dry nose or throat – dryness or soreness may occur but usually improves over time.
  • Sneezing after use – a brief reaction that normally passes quickly.


Rare but serious (seek urgent medical advice):

  • Severe allergic reaction (anaphylaxis) – symptoms include swelling of the face, lips, tongue, or throat, difficulty breathing, or a sudden rash. This is extremely rare but requires immediate medical attention.
  • Eye pain or vision changes – may be a sign of increased eye pressure and should be assessed promptly.


Most people tolerate Dymista well, and side effects (if they do occur) are usually mild. If you are worried about any symptoms, or if they do not improve, speak to your doctor, pharmacist, or prescriber.

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet provided with your medicine for full details. If you experience severe or worrying symptoms, seek medical advice straight away. In an emergency, call 999 or go to A&E.

Warnings

Dymista may not be suitable if you:

  • Are allergic to azelastine, fluticasone, or any ingredients in the spray
  • Have frequent nosebleeds or recent nasal surgery
  • Have untreated infections in the nose or sinuses
  • Are pregnant or breastfeeding (seek advice first)


Avoid driving or operating machinery if you experience drowsiness after use.

Frequently asked questions

  • What is Dymista and how does it work?

    Dymista is a combination nasal spray containing azelastine hydrochloride (an antihistamine) and fluticasone propionate (a corticosteroid). Together, they reduce inflammation and block histamine to relieve congestion, sneezing, itching and runny nose. It is often used when symptoms are more severe or not controlled by single-ingredient sprays.

  • How quickly does Dymista start working?

    Many people feel relief within minutes because of the azelastine component, while the fluticasone builds stronger control over a few days. This combination makes Dymista useful for both fast relief and longer-term stability, especially during high-pollen seasons.

  • What symptoms does Dymista help with?

    Dymista targets a wide range of nasal allergy symptoms including congestion, sneezing, runny nose, itching, sinus pressure and post-nasal drip. The dual action makes it effective for people whose symptoms flare rapidly or persist despite antihistamines or steroid sprays alone.

  • How do I use Dymista correctly?

    Shake the bottle well, tilt your head slightly forward and spray into each nostril as directed. Aim the nozzle outward toward the ear rather than the septum to reduce irritation. Consistent daily use offers the best control, especially when allergens are unavoidable.

  • Who should avoid using Dymista?

    Dymista may not be suitable if you are allergic to azelastine or fluticasone, have untreated nasal infections, recently had nasal surgery or take certain medicines affecting steroid levels. A clinician should assess suitability during pregnancy or breastfeeding.

  • What side effects can Dymista cause?

    Common side effects include a bitter taste, mild nosebleeds, nasal dryness and occasional drowsiness from azelastine. Irritation often improves with better technique. If symptoms persist, a clinician may suggest adjusting the dose or switching treatment.

  • Is Dymista stronger than a steroid spray alone?

    Yes. Dymista combines an antihistamine with a steroid, offering broader control than fluticasone alone. It is often recommended when symptoms remain troublesome despite regular use of single-ingredient sprays. A clinician may also suggest this for fast relief plus inflammation control.

  • Why does Dymista sometimes taste bitter and how can I reduce it?

    The bitter taste comes from azelastine in Dymista dripping toward the throat after spraying. Tilting your head forward, spraying gently and avoiding deep sniffing reduces this effect. Many people also find that taking a sip of water after use removes the aftertaste completely.

  • Is Dymista suitable for severe, year-round allergies?

    Yes. Dymista is often used for perennial allergies caused by dust mites, pets or mould. Its dual-action formula provides consistent control when symptoms are present most days of the year. Regular reviews help ensure it remains the most appropriate option.

  • Can Dymista help with sinus pressure or facial fullness?

    Many people find Dymista improves sinus pressure because fluticasone reduces swelling inside the nose and sinus openings. This can ease feelings of heaviness or fullness, especially during allergy flare-ups. Severe or one-sided sinus symptoms should be assessed clinically.

  • Can Dymista make you drowsy?

    Dymista can sometimes cause mild drowsiness because of the azelastine component. If this happens, using it in the evening may help. Avoid alcohol or other sedating medicines until you understand how it affects you, especially during the first few doses.

  • Can I combine Dymista with oral antihistamines during peak allergy season?

    Yes. Some people benefit from pairing Dymista with an oral antihistamine such as fexofenadine when symptoms are extremely strong. This approach can help manage eye symptoms and intense itching while Dymista controls nasal inflammation. Always follow clinician advice.

  • Is Dymista safe for long-term daily use?

    Many people use Dymista (azelastine + fluticasone) long term, particularly for year-round allergies. Regular reviews ensure the dose remains appropriate and help monitor for rare steroid-related effects such as persistent dryness or mild nosebleeds.

  • What should I do if Dymista irritates my nose or feels too strong?

    If Dymista causes dryness or irritation, reviewing technique, using saline before spraying or alternating nostrils may help. A clinician can also advise whether reducing frequency or switching to a single-ingredient spray is better suited to your symptoms.

  • Why might Dymista stop working as well?

    Reduced benefit usually relates to inconsistent use, incorrect technique or a sudden rise in allergen levels. Reviewing how you spray, rinsing with saline beforehand or adjusting your regimen during high-pollen periods often restores control. Persistent symptoms require clinical review.