• Starts working in 30 minutes to relieve allergy symptoms
  • Effective for hayfever, pet, and dust allergies
  • Drowsy formula can support better rest at night

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Overview

When allergies strike suddenly — from hayfever, pet dander, or even an insect bite — the itching, sneezing, and watery eyes can feel overwhelming. Piriton tablets provide quick, effective relief so you can get back to feeling comfortable. As one of the UK’s most trusted antihistamines, Piriton is particularly helpful for fast-acting relief when symptoms appear without warning.

This medicine requires a secure online consultation with a UK-registered prescriber, and will only be supplied if clinically appropriate.


What is Piriton


Piriton contains chlorphenamine maleate, a first-generation antihistamine that has been trusted in the UK for over 50 years. It works by blocking histamine, the chemical responsible for allergy symptoms such as sneezing, itching and skin irritation. Unlike newer non-drowsy antihistamines, Piriton may cause drowsiness, which can actually be helpful for managing night-time allergy symptoms and improving rest.

Piriton is widely used to relieve hay fever (seasonal allergic rhinitis), allergies to dust or pets, and skin reactions such as hives, itching or insect bites. It can also be taken for mild food allergies (non-anaphylactic) to help ease discomfort.

Relief begins in as little as 30 minutes, with effects lasting for around 4–6 hours. Because it can be taken during the day or at night (with drowsiness possible), Piriton is a flexible option for those looking for fast and effective allergy relief.

Directions

  • Adults and children over 12: One tablet every 4–6 hours as needed, up to a maximum of 6 tablets in 24 hours
  • Children aged 6–12: Half a tablet every 4–6 hours, up to 3 full tablets in 24 hours
  • Do not exceed the stated dose


Always follow prescriber or pharmacist advice.

Side Effects

Like all medicines, Piriton (chlorphenamine maleate) can cause side effects, although not everyone will experience them. Most are mild and temporary, but some may require medical attention.

Common (may affect up to 1 in 10 people):

  • Drowsiness or sleepiness – this is the most frequent side effect of Piriton. For some people, this can be useful at night, but it may interfere with activities during the day. Avoid driving or operating machinery until you know how the medicine affects you.
  • Dry mouth – a dry or uncomfortable feeling in the mouth is fairly common. Drinking water regularly or chewing sugar-free gum can help.
  • Dizziness – some people may feel light-headed. Rising slowly from sitting or lying down can reduce this effect.
  • Blurred vision – temporary visual changes can occur. If this persists, speak to a healthcare professional.

 

Less common (may affect up to 1 in 100 people):

  • Stomach upset – occasional nausea or abdominal discomfort may occur but usually settles on its own.
  • Constipation – some people may notice changes in bowel habits. Increasing fibre and fluids can help.
  • Difficulty concentrating – reduced alertness or difficulty focusing may occur, particularly if drowsiness is present.

 

Rare but serious (seek urgent medical advice):

  • Severe allergic reaction (anaphylaxis) – symptoms include swelling of the face, lips, tongue or throat, difficulty breathing, or a sudden rash. This is very rare but requires immediate medical help.
  • Confusion or hallucinations – these effects are rare and more likely in elderly patients. If they occur, stop taking Piriton and seek medical advice immediately.


Most people tolerate Piriton well, and side effects are generally mild. If you are concerned about any symptoms, or if they do not improve, speak to your doctor, pharmacist, or prescriber.

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine for full details. If you experience severe or worrying symptoms, seek medical advice straight away. In an emergency, call 999 or go to A&E.

Warnings

Piriton may not be suitable if you:

  • Need to drive or operate machinery (it can cause drowsiness)
  • Are taking other sedating medicines or alcohol
  • Have glaucoma, epilepsy, or breathing problems
  • Are pregnant or breastfeeding (seek medical advice before use)
Frequently asked questions
  • What are Piriton tablets and how do they work?

    Piriton (chlorphenamine maleate) is an older antihistamine used for fast relief of hay fever, pet allergies, dust allergies and skin reactions. It works by blocking histamine, the chemical responsible for symptoms such as sneezing, itching and watery eyes. It can also help with allergic skin reactions and hives.

  • How long does Piriton take to work and how long does it last?

    Piriton (chlorphenamine maleate) usually starts working within 30 minutes and provides relief for four to six hours. Because it acts quickly, it is useful for sudden allergy symptoms or unexpected reactions. Many people use it alongside non-drowsy antihistamines when rapid relief is needed.

  • Why do Piriton tablets cause drowsiness?

    Piriton (chlorphenamine maleate) is a sedating antihistamine that crosses into the brain more easily than modern non-drowsy medicines such as loratadine or cetirizine. This can cause sleepiness, slower reactions and reduced alertness. Avoid driving or operating machinery until you know how it affects you.

  • What symptoms can Piriton help with?

    Piriton (chlorphenamine maleate) helps relieve sneezing, runny nose, watery eyes, itching and swelling caused by allergies such as hay fever, pet allergies, dust exposure and hives. It is also useful for sudden allergic reactions, insect bites and mild food-related reactions when fast relief is needed.

  • Who should not take Piriton?

    Avoid Piriton (chlorphenamine maleate) if you have severe liver disease, glaucoma, prostate enlargement causing urinary issues, or if you take medicines that cause strong drowsiness. It shouldn’t be combined with alcohol or sedatives. A pharmacist can advise if you have other medical conditions.

  • Can I take Piriton with other allergy treatments?

    Yes. Piriton (chlorphenamine maleate) can be used with nasal sprays or antihistamine eye drops for stronger control. It should not be combined with another oral antihistamine, although some people switch between non-drowsy daytime tablets and Piriton at night.

  • Is Piriton safe in pregnancy or breastfeeding?

    Piriton (chlorphenamine maleate) may be used in pregnancy when advised by a clinician, but many prefer non-drowsy antihistamines first. During breastfeeding, small amounts may pass into milk and cause drowsiness in infants, so medical guidance is essential before use.

  • Can Piriton help with allergic reactions or swelling?

    Yes. Piriton (chlorphenamine maleate) is often used for reactions involving itching, swelling or redness, including mild food reactions, pet allergies and environmental exposure. It works quickly to calm histamine release, but severe reactions always require emergency care. If swelling is frequent, speak to a clinician for long-term management advice.

  • Can children take Piriton safely?

    Children over one year old can usually take Piriton (chlorphenamine maleate) if dosed correctly. Syrup is often used for younger age groups, while tablets suit older children. Always follow age-specific instructions and seek advice if symptoms worsen or breathing difficulties occur.

  • Can Piriton help with insect bites or stings?

    Yes. Piriton (chlorphenamine maleate) can reduce itching, redness and swelling caused by insect bites and stings. Because it works quickly, it is useful for outdoor exposure or sudden flare-ups. For severe swelling or breathing problems, seek emergency care.

  • Can I drive or operate machinery after taking Piriton?

    Driving should be avoided after taking Piriton (chlorphenamine maleate) because it commonly causes drowsiness, slower reactions and reduced concentration. These effects can last several hours. If you feel sleepy or mentally foggy, wait until you are fully alert before driving or using tools.

  • Can Piriton be used at night to help sleep during allergies?

    Yes. Many people use Piriton (chlorphenamine maleate) at night because the drowsiness can help settle symptoms that disrupt sleep. It may be paired with a non-drowsy antihistamine taken earlier in the day for full coverage. Avoid alcohol and other sedatives when using Piriton at night.

  • Why might Piriton be chosen instead of non-drowsy antihistamines?

    Some people find Piriton (chlorphenamine maleate) works better for sudden itching, hives or reactions that appear quickly. It is also preferred when drowsiness is useful, such as bedtime symptoms. Non-drowsy antihistamines may be better for daily control, but Piriton offers fast relief in specific situations.

  • Can Piriton be combined with nasal sprays or eye drops for stronger relief?

    Yes. Piriton (chlorphenamine maleate) can be used with steroid nasal sprays, antihistamine eye drops or saline sprays when symptoms are more severe. This combination can help control congestion, sneezing or itchy eyes more effectively.

  • What should I do if Piriton makes me too sleepy?

    If Piriton (chlorphenamine maleate) causes significant drowsiness, take the tablet earlier in the evening, reduce how often you use it or switch to a non-drowsy antihistamine. Avoid alcohol and sedatives, and speak to a clinician if sleepiness affects daily activities.