• Relieves IBS cramps and bloating by relaxing gut muscles.
  • Targets symptoms directly without causing drowsiness.
  • Well-tolerated for long-term management of recurring flare-ups.

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Overview

IBS cramps, bloating, and discomfort can disrupt your day without warning. Colofac Tablets (135mg & 200mg) are the trusted branded form of mebeverine, working directly on the bowel muscles to ease spasms and restore comfort. With Colofac, you can manage flare-ups discreetly and feel more confident getting on with life.
At SwiftMedi, all requests are reviewed by a UK-registered prescriber via secure online consultation, with fast, discreet delivery to your door.


What is Colofac


Colofac contains mebeverine hydrochloride, an antispasmodic medicine that relaxes the smooth muscle of the gut.

It is commonly prescribed for:

  • Irritable Bowel Syndrome (IBS)
  • Chronic irritable colon
  • Spastic constipation
  • Other conditions involving painful gut spasms


By reducing spasms without slowing normal bowel movement, Colofac relieves:

  • Abdominal pain and cramps
  • Bloating and trapped wind
  • Urgency linked to IBS flare-ups

Directions

Colofac 135mg:

  • Usual dose: 1 tablet three times a day
  • Take 20 minutes before meals with water


Colofac MR 200mg (Modified Release):

  • Usual dose: 1 capsule twice a day (morning and evening)
  • Swallow whole with water — do not crush or chew

Side Effects

Like all medicines, Colofac can cause side effects, although not everyone will experience them. Side effects are uncommon and usually mild.

Uncommon (may affect up to 1 in 100 people):

  • Mild skin rash or itching
  • Indigestion or nausea


Rare but serious (seek medical help immediately):

  • Allergic reaction (swelling, rash, difficulty breathing)
  • Severe blistering rash or skin reaction


Most people tolerate Colofac well, and side effects (if they do occur) are rare. If you are concerned about any symptoms, or they do not improve, speak to your doctor, pharmacist, or prescriber.

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet provided with your medicine for full details. If you experience severe or worrying symptoms, seek medical advice straight away. In an emergency, call 999 or go to A&E.

Warnings

Colofac may not be suitable if you:

  • Are under 18 years old
  • Are pregnant or breastfeeding (unless approved by your prescriber)
  • Have lactose intolerance (some formulations may contain lactose)
  • Have had an allergic reaction to mebeverine or similar medicines


Always disclose your medical history and current medicines during your consultation.

FAQ's

Is Colofac the same as Mebeverine?
Yes — Colofac is a branded version of mebeverine hydrochloride.

Which is better, Colofac 135mg or 200mg?
Both contain mebeverine. The 200mg modified-release capsules are taken twice a day, which some people find more convenient.

How quickly does Colofac work?
Relief can start within hours, but regular use may be needed for full effect.

Can I take Colofac long term?
Yes, many people use Colofac safely for long-term IBS management under prescriber guidance.

Does Colofac cure IBS?
No — it manages symptoms like cramps and bloating but does not cure IBS.

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