• Relieves painful gut spasms
  • Works directly on the colon muscle
  • Suitable for long-term management of IBS symptoms

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Overview

Living with IBS often means unpredictable cramps, bloating, and rushing to the toilet at the worst times. Mebeverine 135mg Tablets are designed to gently calm the bowel muscles, easing spasms and restoring comfort, so you can feel more confident and in control of your day.

At SwiftMedi, every request is reviewed by a UK-registered prescriber via a secure online consultation, with discreet delivery straight to your door.


What is Mebeverine 


Mebeverine is a well-established antispasmodic medicine used to treat Irritable Bowel Syndrome (IBS) and other digestive disorders involving cramping and bloating.

It works by relaxing the smooth muscle in the gut, reducing spasms without slowing down normal bowel function. This makes it particularly useful for people whose IBS alternates between constipation and diarrhoea.

Mebeverine helps relieve:

  • Abdominal cramps and stomach pain
  • Bloating and discomfort
  • Urgent or unpredictable bowel movements

Directions

  • The usual adult dose is 1 tablet (135mg) three times a day.
  • Take tablets 20 minutes before meals with a glass of water.
  • Swallow whole - do not chew or crush.
  • Do not exceed the recommended dose.


Not recommended for children under 18. Always follow your prescriber’s advice.

Side Effects

Like all medicines, Colofac can cause side effects, although not everyone gets them. Most people tolerate it well and side effects are rare.

Uncommon (may affect up to 1 in 100 people):

  • Mild skin rash or itching
  • Indigestion or feeling sick (nausea)

Rare but serious (seek medical advice immediately):

  • Signs of a severe allergic reaction: swelling of the face, lips, tongue or throat, or difficulty breathing.
  • A severe skin rash with blistering or peeling.

 

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine. If you notice anything unusual or concerning, stop using the medicine and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

Mebeverine may not be suitable if you:

  • Are under 18 years old
  • Are pregnant or breastfeeding (unless advised by a prescriber)
  • Have rare hereditary problems such as galactose intolerance or glucose-galactose malabsorption (due to lactose content in some brands)
  • Have ever had an allergic reaction to Mebeverine or any of the ingredients


Always disclose your medical history and current medicines during your consultation.

Frequently asked questions
  • What is Mebeverine and how does it work?

    Mebeverine is an antispasmodic medicine that relaxes the muscles of the gut to help control IBS-related cramping and discomfort. It reduces bowel overactivity, making flare ups less intense and more manageable. It is often chosen when cramps occur after meals or during stress.

  • What IBS symptoms does Mebeverine help with?

    Mebeverine mainly helps with abdominal cramps, gripping pains and discomfort triggered by bowel spasms. It does not directly treat diarrhoea or constipation, but reducing spasms often makes these symptoms easier to manage as part of a wider IBS plan.

  • How long does Mebeverine take to work?

    Mebeverine starts helping within one to three hours, although full symptom improvement may take a few days of consistent use. Many people take it before meals to prevent cramping after eating.

  • How do I take Mebeverine safely?

    The usual adult dose is one tablet taken twenty minutes before meals, up to three times daily. Swallow the tablets whole with water. Do not exceed the recommended daily dose, and review treatment if symptoms persist.

  • What are the common side effects of Mebeverine?

    Mebeverine is generally well tolerated. Mild side effects can include nausea, headaches or indigestion. Serious reactions are uncommon, but stop the medicine and seek help if you experience allergic symptoms such as swelling or difficulty breathing.

  • Who should avoid Mebeverine?

    Mebeverine is not suitable for people with severe bowel conditions such as paralytic ileus or for those who have previously had an allergic reaction to antispasmodics. Speak to a clinician if you are pregnant, breastfeeding or take multiple gut-acting medicines.

  • Is Mebeverine better than Buscopan for IBS cramps?

    Mebeverine and Buscopan work differently. Mebeverine is often preferred for meal-related cramps and general gut sensitivity, while Buscopan may help more with sudden, sharp spasms. Some patients benefit from trying both at different times to see which gives better relief.

  • Does Mebeverine help diarrhoea or constipation?

    Mebeverine does not directly treat diarrhoea or constipation because it targets muscle spasms rather than bowel speed. However, by calming the gut, some people notice fewer urgency episodes or more stable bowel habits. If diarrhoea or constipation persist, another treatment may be needed.

  • Can Mebeverine reduce bloating and trapped wind?

    Mebeverine may help indirectly by relaxing bowel muscles, which can reduce the feeling of tightness linked to bloating. For stronger bloating relief, pairing it with peppermint oil or dietary adjustments often produces better results.

  • Can I take Mebeverine with food or drink?

    Mebeverine works best when taken before meals to prevent post-meal cramps. It can be taken with water, and there are no specific food restrictions. Limit alcohol if it worsens symptoms or contributes to flare ups.

  • Can I use Mebeverine regularly for long-term IBS?

    Yes. Mebeverine can be used long term if it continues to provide relief. If you still have frequent symptoms, a clinician may recommend a different antispasmodic or a tailored IBS treatment plan.

  • Can I combine Mebeverine with other IBS treatments?

    Many people safely use Mebeverine alongside peppermint oil, probiotics or dietary adjustments. Since they work in different ways, a combined approach often gives more consistent symptom control.

  • What if Mebeverine does not improve my symptoms?

    If symptoms continue, another antispasmodic or a prescription IBS medicine may suit you better. Persistent pain, weight loss or bleeding should always be assessed as these are not typical IBS symptoms.

  • Does stress affect how well Mebeverine works?

    Stress can trigger stronger gut sensitivity and more muscle spasms, which can make IBS harder to control. Mebeverine still helps, but pairing it with stress-management techniques often leads to more reliable symptom control.

  • Is Mebeverine safe to use alongside probiotics or fibre supplements?

    Yes. Mebeverine works on gut muscles, while probiotics and fibre work on digestion and stool consistency. Using them together can help you target several IBS symptoms at once.

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