• Resets your body clock naturally after long flights
  • Available in 2mg (off-label for jet lag) and 3mg strengths 
  • Non-addictive and clinically proven for sleep adjustment

How it works?

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Overview

Jet lag happens when your internal body clock (circadian rhythm) is out of sync with local time after crossing multiple time zones. While symptoms usually pass, they can be disruptive — especially if you’re travelling for work, an event, or a holiday.

What is Melatonin

Melatonin is a naturally occurring sleep hormone. By supplementing melatonin at the right time, it helps reset your sleep–wake cycle, making it easier to drift off at night and feel more awake during the day.

  • Circadin 2mg (modified-release): Licensed in the UK for insomnia in over-55s, but commonly prescribed off-label for short-term jet lag.
  • Melatonin 3mg: Available in some formulations and used off-label in the UK.


Both strengths work by gently restoring melatonin levels to support a faster adjustment to new time zones.

Directions

  • Take 1 tablet 1–2 hours before your intended bedtime in the new time zone for up to 5 days.
  • Melatonin should be swallowed whole with water — do not crush or chew.
  • Use for a few nights after travel, or as directed by your prescriber.
  • Avoid alcohol, as it reduces effectiveness.

Side Effects

Most people tolerate Melatonin well. Side effects, if they occur, are usually mild and short-lived.

Common (may affect up to 1 in 10 people):

  • Headache
  • Drowsiness or fatigue
  • Nausea


Uncommon (may affect up to 1 in 100 people):

  • Dizziness
  • Irritability or mood changes
  • Abdominal pain


Rare but serious (seek urgent medical help):

  • Severe allergic reaction (rash, swelling, difficulty breathing)


Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine for full details. If you notice anything unusual or concerning, stop taking Circadin and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

  • For short-term use only unless otherwise directed.
  • Avoid driving or operating machinery if you feel drowsy.
  • Do not use if allergic to melatonin or any ingredients.
  • Speak to your prescriber before use if you are pregnant, breastfeeding, or taking other medicines that affect sleep (such as sedatives or antidepressants).
  • Circadin 2mg is licensed in the UK for insomnia but often used off-label for jet lag.