• Works within 30 minutes
  • Proven effective migraine treatment
  • Relieves pain, nausea and sensitivity together

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Overview

When a migraine strikes, fast relief can make all the difference. Rizatriptan is a trusted triptan medication that works by calming overactive brain signals and narrowing widened blood vessels - stopping migraines in their tracks. Taken at the first sign of attack, Rizatriptan helps ease pain, nausea, and sensitivity so you can get back to your day with confidence.


All requests at SwiftMedi are carefully reviewed by a UK-registered prescriber through a secure online consultation, with discreet delivery direct to your door.


What is Rizatriptan


Rizatriptan belongs to a class of medicines called triptans (5-HT1 receptor agonists). It is designed specifically for the treatment of acute migraine attacks, with or without aura.

Unlike painkillers, Rizatriptan targets the underlying migraine process by:

  • Narrowing widened blood vessels in the brain
  • Calming overactive nerve pathways
  • Reducing pain, nausea, and sensitivity to light and sound


It is not intended for migraine prevention, but for treatment of an attack once it begins.

Directions

  • Take one 10mg tablet at the first sign of a migraine attack.
  • If the migraine returns, a second dose may be taken after 2 hours.
  • Do not exceed 2 tablets (20mg) in 24 hours.
  • Swallow with water. Orally disintegrating tablets (ODT) may be available that dissolve on the tongue.


Not suitable for use in children under 18. Always follow your prescriber’s advice.

Side Effects

Like all medicines, Rizatriptan can cause side effects, although not everyone gets them. Most side effects are short-lived and mild.

Common (may affect up to 1 in 10 people):

  • Dizziness or sleepiness
  • Tiredness or weakness
  • Flushing or warm sensations

 

Less common (may affect up to 1 in 100 people):

  • Dry mouth
  • Indigestion or nausea

 

Rare but serious (seek medical advice immediately):

  • Chest pain, pressure or tightness
  • Signs of a severe allergic reaction: swelling of the face, lips, tongue or throat, or difficulty breathing
  • Irregular heartbeat or palpitations

 

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine. If you notice anything unusual or concerning, stop using the medicine and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

Rizatriptan may not be suitable if you:

  • Are under 18 years or over 65
  • Are pregnant or breastfeeding (unless advised)
  • Have heart disease, uncontrolled high blood pressure, or history of stroke
  • Are taking other migraine medicines (including other triptans or ergotamine)
  • Use SSRIs or SNRIs (antidepressants) - risk of serotonin syndrome
  • Have severe liver or kidney problems


Always disclose your full medical history during consultation.

Frequently asked questions
  • What is rizatriptan and how does it work?

    Rizatriptan is a triptan medicine used to treat migraine attacks by narrowing swollen blood vessels and calming overactive pain pathways. It works best when taken early in the headache phase. Many people use it when migraines are strong, sudden or associated with nausea.

  • How quickly does rizatriptan start working for migraines?

    Rizatriptan starts working within 30 minutes for many people and is often considered one of the faster triptans. Taking it at the first sign of migraine pain usually improves results. Melt tablets may help if swallowing is difficult due to nausea.

  • How do I take rizatriptan safely?

    Take one dose at the start of a migraine and a second dose only if symptoms return, leaving the recommended gap stated on the label. Do not exceed the maximum daily or monthly limits. Using it too often may cause medication-overuse headache.

  • What side effects can rizatriptan cause?

    Common effects of Rizatriptan include tingling, tightness, warm sensations, dizziness or tiredness. These are usually short-lived. Rare symptoms such as chest discomfort, shortness of breath or severe allergic reactions need urgent medical attention.

  • Who should not take rizatriptan?

    Avoid rizatriptan if you have heart disease, stroke history, uncontrolled high blood pressure or certain rhythm problems. It may also be unsuitable if you take particular antidepressants. A clinician will check your medical background before prescribing it.

  • Can I take rizatriptan with ibuprofen or paracetamol?

    Yes. Many people combine rizatriptan with ibuprofen or paracetamol for stronger early relief. Avoid mixing it with other triptans or migraine-specific medicines on the same day unless advised. Always use combination therapy cautiously to avoid overuse.

  • What should I do if rizatriptan doesn’t fully stop my migraine?

    If one dose helps only partly, a second dose can be taken after the required gap. Persistent symptoms may mean you need a different triptan, a faster formulation, or preventive medication. Reviewing timing and migraine triggers also helps.

  • Is rizatriptan stronger or faster than sumatriptan?

    Rizatriptan works more quickly for some people, while sumatriptan may be longer lasting for others. Effectiveness varies based on how early it’s taken, attack severity and individual response. People who struggle with slow onset often prefer rizatriptan as a faster option.

  • Can rizatriptan help migraines that start with aura?

    Yes, but it should be taken when the headache begins rather than during the aura phase. Treating too early may reduce effectiveness. People with frequent aura-related migraines may need a tailored treatment plan from a clinician.

  • Can I take rizatriptan if I feel sick or vomit with migraines?

    Yes. Rizatriptan melt tablets dissolve on the tongue and can be helpful if nausea makes swallowing difficult. Taking it early often prevents worsening sickness. If vomiting is severe, adding anti-nausea medicine may improve results.

  • Does rizatriptan interact with antidepressants or anxiety medicines?

    Rizatriptan can interact with certain antidepressants, especially SSRIs, SNRIs and MAOIs. Most people can still use it safely with monitoring, but medical review is important to minimise risks. Never start a new psychiatric medicine without checking for interactions.

  • Can I take rizatriptan during my menstrual migraines?

    Yes. Rizatriptan is frequently used for menstrual migraines, which can be more severe and difficult to treat. Some clinicians recommend taking it at the very first sign of pain or using short-term preventive medicines during your cycle.

  • Can rizatriptan be used if migraines keep waking me up at night?

    Yes. If a migraine starts overnight, taking rizatriptan as soon as you wake can still help shorten the attack. Night-time migraines may require reviewing triggers, sleep patterns or alternative treatments if they happen regularly.

  • How many days per month can I safely take rizatriptan?

    Most people should limit triptan use to no more than 8–10 days per month to avoid medication-overuse headache. If you need it more often, preventive treatment may be more appropriate.

  • Why does my migraine return hours after taking rizatriptan?

    Some migraines respond quickly but return as the attack develops. This can happen if medicine is taken late or the trigger is ongoing. A second dose may help, but frequent recurrence may need a different triptan or preventive therapy.