• Dissolves in seconds without water
  • Starts targeting migraine pain in 15 minutes
  • Relieves pain, nausea and sensitivity together

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Overview

When a migraine strikes, swallowing a tablet can feel impossible. Zolmitriptan Orodispersible Tablets melt gently on your tongue without the need for water, making them an easy and effective option for migraine relief. By tackling the brain changes that trigger migraines, they help ease pain, nausea, and sensitivity - often within 45 minutes - so you can find comfort and get back to what matters.


Every request at SwiftMedi is reviewed by a UK-registered prescriber via a secure online consultation, with discreet delivery to your door.


What are Zolmitriptan Orodispersible Tablets


Zolmitriptan Orodispersible Tablets belong to the triptan family (5-HT1 receptor agonists) and are used for the acute treatment of migraine attacks, with or without aura.

What makes this form unique:

  • No need for water - dissolves directly on the tongue
  • Ideal if you feel sick, vomit, or cannot swallow during an attack
  • Portable, discreet, and convenient to use anywhere


Like other triptans, Zolmitriptan works by:

  • Narrowing widened blood vessels in the brain
  • Blocking overactive pain signals
  • Relieving migraine symptoms such as headache, nausea, and light/sound sensitivity

Directions

  • Place one 2.5mg or 5mg tablet on your tongue at the first sign of a migraine.
  • Allow it to dissolve - no water is needed.
  • If symptoms return, a second dose may be taken after 2 hours.
  • Do not exceed 10mg in 24 hours.


Not suitable for children under 18. Always follow your prescriber’s guidance.

Side Effects

Like all medicines, Zolmitriptan can cause side effects, although not everyone gets them.

Common (may affect up to 1 in 10 people):

  • Sleepiness or tiredness
  • Dizziness
  • Flushing or a feeling of warmth

 

Less common (may affect up to 1 in 100 people):

  • Tingling or a feeling of heaviness
  • Dry mouth or indigestion
  • Muscle aches

 

Rare but serious (seek medical advice immediately):

  • Severe chest pain, pressure or tightness
  • Signs of a severe allergic reaction: swelling of the face, lips, tongue or throat, or difficulty breathing
  • Irregular heartbeat or palpitations

 

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine. If you notice anything unusual or concerning, stop using the medicine and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

Zolmitriptan Orodispersible Tablets may not be suitable if you:

  • Are under 18 or over 65
  • Are pregnant or breastfeeding (unless advised)
  • Have heart disease, uncontrolled blood pressure, or history of stroke
  • Are taking other triptans or ergotamine medicines
  • Are on SSRIs, SNRIs, or MAOIs (antidepressants)
  • Have liver or kidney problems
  • Always give your prescriber your full medical history.
Frequently asked questions
  • What are zolmitriptan orodispersible tablets and how do they treat migraines?

    Zolmitriptan orodispersible tablets dissolve on the tongue and treat migraines by calming pain pathways and narrowing widened blood vessels. They are ideal when swallowing is difficult or nausea appears early in an attack. Because they work without water, they offer fast and convenient relief in many situations.

  • How fast do zolmitriptan orodispersible tablets work?

    They typically begin working within 20-45 minutes. Since they dissolve in the mouth, they may absorb faster than standard tablets, especially during attacks that slow digestion. Taking them as soon as symptoms begin usually leads to better overall relief and reduces the chance of the migraine progressing.

  • How should I take zolmitriptan orodispersible tablets correctly?

    Place the tablet on your tongue and let it dissolve before swallowing. You do not need water. Take it early at the first sign of migraine pain to prevent symptoms escalating. Avoid repeating doses unless instructed, and follow the daily maximum set by your prescriber.

  • What side effects can zolmitriptan orodispersible tablets cause?

    Some people notice tingling, warmth, dizziness or temporary taste changes when the tablet dissolves. These effects are usually short-lived. Seek urgent help if you develop chest pain, severe tightness or breathing problems. If side effects occur frequently or become bothersome, another triptan may suit you better.

  • Who should not take zolmitriptan orodispersible tablets?

    They are not suitable for people with heart disease, previous stroke, uncontrolled high blood pressure or certain circulatory conditions. They may also interact with antidepressants or migraine preventers. A clinician will assess your medical history and regular medicines before prescribing.

  • Can I take a second zolmitriptan orodispersible tablet if my migraine returns?

    Yes. If symptoms return after initial relief, a second tablet may be taken after the recommended interval, provided you stay within the daily maximum dose. Many people find this useful for migraine attacks that briefly improve then flare again.

  • Are zolmitriptan orodispersible tablets as effective as standard Zomig tablets?

    Yes. They provide the same migraine relief and are often preferred when nausea, travel or difficulty swallowing make standard tablets less suitable. Their quick-dissolve design can also help people treat attacks more promptly. Effectiveness varies between individuals.

  • Do zolmitriptan orodispersible tablets work well when migraines affect the stomach?

    Yes. When migraines slow stomach emptying or cause strong nausea, orodispersible tablets can be more effective because they bypass the digestive process. This allows earlier absorption and often results in faster symptom relief than standard tablets during gut-related migraine symptoms.

  • Can I use zolmitriptan orodispersible tablets if I don’t have water available?

    Yes. They are ideal for situations such as commuting, night-time attacks or travelling when water is not easy to access. The tablet dissolves directly on the tongue, allowing rapid treatment without needing to swallow a traditional tablet.

  • Why do zolmitriptan orodispersible tablets sometimes taste slightly bitter?

    A brief bitter taste is normal as the tablet dissolves. This does not affect how well the medicine works and usually fades within seconds. A small sip of water afterwards can help if the taste lingers, but it is not required for effectiveness.

  • Are zolmitriptan orodispersible tablets better for migraines that start suddenly?

    Yes. Because absorption can begin earlier than with standard tablets, the orodispersible version is helpful for sudden, fast-building migraines. Treating early is key for preventing severe symptoms, and orodispersible tablets make prompt dosing easier.

  • Can zolmitriptan orodispersible tablets help when migraines make swallowing difficult?

    Yes. Many people find swallowing hard during attacks due to nausea or throat tightness. Orodispersible tablets dissolve without needing to swallow a full tablet, making them easier to take during intense symptoms. This often leads to more reliable relief.

  • Are zolmitriptan orodispersible tablets suitable for frequent travel-related migraines?

    Yes. Their convenience, compact packaging and ability to take them without water make them an excellent option for travel. They work well during flights, long journeys or busy commutes where migraines may develop quickly and swallowing tablets is inconvenient.

  • How should I store zolmitriptan orodispersible tablets when carrying them with me?

    Keep the tablets in their original foil strips to protect them from moisture. Orodispersible tablets are more sensitive to humidity, so avoid leaving opened strips in warm or damp places. Many people carry spare strips for quick use during early symptoms.

  • What should I do if zolmitriptan orodispersible tablets only partly relieve my symptoms?

    You may take a second dose after the recommended interval if symptoms return or only partly improve. If this happens regularly, switching to a different triptan, adjusting timing or exploring preventive options may work better.