• Powerful pain relief with stomach protection
  • Long-lasting relief from various pain types
  • Trusted option when other NSAIDs aren't suitable

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Overview

Celecoxib (brand name Celebrex) is a powerful anti-inflammatory painkiller that provides long-lasting relief while being gentler on the stomach than traditional NSAIDs.
Commonly prescribed for back pain, muscle aches, dental pain, and period cramps, it’s a trusted option for people who need effective pain control with fewer stomach-related side effects.


What is Celecoxib 

Celecoxib belongs to the family of medicines known as NSAIDs (non-steroidal anti-inflammatory drugs), but with a difference. Unlike standard NSAIDs that block both COX-1 and COX-2 enzymes, celecoxib selectively blocks COX-2 - the enzyme responsible for pain and inflammation.

This selective action means celecoxib can:

  • Provide strong pain relief for conditions such as muscle pain, back pain, dental pain, and period pain
  • Reduce swelling and stiffness, helping you move more freely
  • Carry a lower risk of stomach irritation and ulcers compared with traditional NSAIDs


Celecoxib gives you powerful, targeted pain relief — without as much of the stomach irritation linked to older painkillers.

Directions

  • Usual adult dose: 200mg once daily, or 100mg twice daily, depending on condition.
  • Always take with or after food to support stomach comfort.
  • Use the lowest effective dose for the shortest possible time.
  • Swallow capsules whole with water — do not crush or chew.

Side Effects

Like all medicines, celecoxib can cause side effects, but not everyone gets them.

Common (may affect up to 1 in 10 people):

  • Indigestion or stomach pain
  • Headache
  • Nausea or diarrhoea


Uncommon (may affect up to 1 in 100 people):

  • Dizziness or sleep problems
  • Swelling in the legs or feet (fluid retention)
  • Increased blood pressure


Rare but serious (seek urgent help):

  • Severe stomach pain, vomiting blood, or black stools (stomach bleeding)
  • Chest pain or shortness of breath (heart-related side effects)
  • Severe allergic reaction (swelling, rash, difficulty breathing)


Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine for full details. If you notice anything unusual or concerning, stop taking celecoxib and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

  • Not suitable if you have a history of heart attack, stroke, or serious circulation problems.
  • Avoid if allergic to celecoxib, sulfonamides, aspirin, or other NSAIDs.
  • Not recommended in pregnancy or while breastfeeding.
  • Inform your prescriber if you have high blood pressure, high cholesterol, diabetes, or if you smoke — as celecoxib can slightly increase heart risks.
  • Use with caution if you are taking blood thinners, SSRIs, or other anti-inflammatory medicines.

FAQ's

How is celecoxib different from naproxen or ibuprofen?
Celecoxib targets the COX-2 enzyme, which reduces inflammation and pain while causing less irritation to the stomach lining.

How quickly does celecoxib work?
Relief usually begins within a few hours, with full effect after regular dosing for a few days.

Can I take celecoxib for period pain?
Yes, it is often prescribed for menstrual cramps, particularly when other NSAIDs have caused stomach irritation.

Is celecoxib safer for the stomach?
Yes — its selective action lowers the risk of stomach irritation compared with traditional NSAIDs. However, some risk remains, especially with long-term use.

Can celecoxib be taken long-term?
It may be used long-term under supervision, but your prescriber will weigh up the benefits against heart and circulation risks.