• Specifically effective for period pain relief
  • Blocks pain and inflammation at the source
  • Also treats muscle, back and dental pain

How it works?

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Overview

Mefenamic acid is a proven prescription painkiller that’s often used for period cramps, easing the abdominal and back pain that so often disrupt your day. By targeting the cause of pain and inflammation, it provides fast, reliable relief - not just for menstrual pain, but also for muscle aches, back pain, and dental pain.

 

What is Mefenamic acid

Mefenamic acid is a prescription-only non-steroidal anti-inflammatory drug (NSAID) that works by blocking the body’s production of prostaglandins - natural chemicals that trigger pain, inflammation, and muscle contractions. By reducing these chemicals, mefenamic acid provides effective relief from moderate pain and discomfort.

It is especially effective for period pain (dysmenorrhoea), where it helps ease abdominal cramps, back pain, and pelvic discomfort caused by uterine contractions. Unlike standard painkillers, mefenamic acid doesn’t just dull the pain - it actively reduces the inflammation that causes it, helping you feel more comfortable and in control throughout your cycle.

In addition to menstrual pain, mefenamic acid can also be prescribed for muscle aches, back pain, dental pain, and mild arthritis-related discomfort, offering flexible, targeted relief when ordinary painkillers aren’t enough.

Because it tackles both pain and inflammation, many people find it not only relieves discomfort but also helps restore energy and movement - allowing them to get back to their day with minimal disruption.

Directions

  • Usual adult dose: 500mg initially, followed by 250mg every 6 hours as required.
  • Take with food or milk to reduce stomach irritation.
  • Do not exceed the maximum daily dose recommended by your prescriber.
  • Use the lowest effective dose for the shortest possible time.

Side Effects

Mefenamic acid is generally well tolerated, but side effects may occur.

Common (may affect up to 1 in 10 people):

  • Indigestion or stomach pain
  • Nausea or diarrhoea
  • Heartburn


Uncommon (may affect up to 1 in 100 people):

  • Headache or dizziness
  • Constipation or bloating
  • Rash or itching


Rare but serious (seek urgent help):

  • Severe stomach pain, vomiting blood, or black stools (signs of bleeding)
  • Chest pain or shortness of breath (possible heart-related side effects)
  • Severe allergic reaction (swelling, rash, difficulty breathing)


Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine for full details. If you notice anything unusual or concerning, stop taking mefenamic acid and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

  • Not suitable if you have a history of stomach ulcers, bleeding disorders, severe kidney or liver problems, or certain heart conditions.
  • Avoid if allergic to mefenamic acid, aspirin, or other NSAIDs.
  • Not recommended in late pregnancy.
  • Use with caution if taking blood thinners, corticosteroids, SSRIs, or other NSAIDs.
  • Limit alcohol while taking to reduce risk of stomach irritation.

FAQ's

Why is mefenamic acid prescribed for period pain?
Because it blocks prostaglandins, which trigger uterine contractions, making it especially effective for cramps.

How quickly does mefenamic acid work?
It usually starts to relieve pain within 1 hour, with full effect as regular doses are taken.

Can I use mefenamic acid for back or muscle pain?
Yes, it’s effective for a variety of inflammatory pain conditions, not just period pain.

Is mefenamic acid stronger than ibuprofen?
It is often considered more effective for period pain, but both belong to the same NSAID family.

Can I take mefenamic acid long-term?
It is usually prescribed for short courses. Long-term use should only be under close medical supervision.