• A powerful NSAID for quick and effective pain relief
  • Relieves muscle, back, dental, and period pain
  • Flexible formulations to suit short-term use or ongoing treatment

How it works?

Online Consultation

We ask you to complete a quick and easy consultation and get you started.

Choose condition

We have a selection of treatments available for various conditions.

Express Delivery

You will have complete visibility and control of your delivery.
Notice!

Before ordering this treatment, you may have to complete an online consultation

Overview

Naproxen is a powerful anti-inflammatory painkiller trusted by millions worldwide. Whether it’s back pain that keeps you stiff, muscle aches after injury, a throbbing toothache, or painful period cramps, Naproxen provides fast, reliable relief so you can get back to living your life.
Available in immediate-release for quick relief and gastro-resistant tablets for longer-term comfort.


Living with such pain can drain your energy, interrupt your sleep, and make even simple daily tasks feel overwhelming. Naproxen offers dependable relief from a wide range of painful conditions — including muscle pain, back pain, dental pain, and period cramps.

As part of the NSAID (non-steroidal anti-inflammatory drug) family, Naproxen works by targeting the source of pain and inflammation, not just masking the symptoms. That means less stiffness, reduced swelling, and lasting comfort.

  • Immediate-release tablets act fast, making them ideal for flare-ups.
  • Gastro-resistant tablets are specially designed to protect the stomach, making them suitable for people who need treatment over a longer period.

Directions

  • Typical dose: 250mg–500mg, taken 2–3 times daily with food (dose depends on the condition being treated).
  • Always take with a meal or snack to reduce stomach irritation.
  • Do not exceed the maximum prescribed daily dose.
  • Use the lowest effective dose for the shortest possible time.
  • Gastro-resistant tablets should be swallowed whole — do not crush or chew.

Side Effects

Like all NSAIDs, Naproxen may cause side effects, though many people tolerate it well.

Common (may affect up to 1 in 10 people):

  • Indigestion or stomach pain
  • Heartburn
  • Nausea


Less common (may affect up to 1 in 100 people):

  • Headache or dizziness
  • Diarrhoea or constipation
  • Skin rash or itching


Rare but serious (seek urgent medical help):

  • Severe stomach pain, vomiting blood, or black stools (signs of stomach bleeding)
  • Chest pain or shortness of breath (possible heart-related side effects)
  • Severe allergic reaction (swelling, rash, difficulty breathing)

 

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine for full details. If you notice anything unusual or concerning, stop taking Naproxen and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

  • Not suitable if you have a history of stomach ulcers, bleeding disorders, severe kidney or liver problems, or certain heart conditions.
  • Avoid if allergic to naproxen, aspirin, or other NSAIDs.
  • Not recommended in pregnancy (especially in the last trimester).
  • Limit alcohol while taking naproxen, as it increases stomach irritation.
  • Tell your prescriber if you take blood thinners, corticosteroids, SSRIs, or other NSAIDs.
Frequently asked questions
  • What is naproxen and how does it work?

    Naproxen is an anti-inflammatory painkiller that reduces swelling, stiffness and discomfort. It works by lowering prostaglandins, chemicals that drive inflammation. It is often prescribed when conditions do not respond well to milder pain relief such as paracetamol. 

  • What conditions is naproxen used for?

    Naproxen is commonly used for muscle pain, joint pain, back pain, period pain and inflammatory conditions such as arthritis. It provides longer-lasting relief compared with many standard anti-inflammatory tablets and is taken one or two times a day.

  • How long does naproxen take to work?

    Naproxen usually starts to ease pain within one hour, though full anti-inflammatory effects may take longer. It lasts around 8–12 hours, which makes it useful for conditions needing steady relief across the day.

  • Is naproxen stronger than ibuprofen?

    Naproxen often lasts longer than ibuprofen, making it helpful for persistent pain such as back pain or menstrual pain. Some people find naproxen more effective, while others respond better to ibuprofen. A clinician can advise which medicine suits your symptoms best.

  • How do I take naproxen safely?

    Take naproxen with food and swallow tablets whole with water. Use the lowest dose for the shortest time needed to control symptoms. Avoid combining it with other anti-inflammatories such as ibuprofen.

  • What are the common side effects of naproxen?

    Common side effects include indigestion, stomach discomfort, heartburn, headache and dizziness. Taking naproxen with food helps reduce stomach irritation. Seek help if you develop black stools, severe abdominal pain or unusual bruising.

  • Who should not take naproxen?

    Naproxen is not suitable if you have stomach ulcers, severe heart disease, kidney problems, active bleeding disorders or if you are pregnant. It may also interact with blood thinners and some blood pressure medicines. Always check with a clinician first.

  • Can I take naproxen with paracetamol?

    Yes. Naproxen and paracetamol work differently, so they can be taken together for stronger relief. Do not take naproxen with ibuprofen or other anti-inflammatories, as this increases stomach and kidney risks.

  • Is prescription naproxen different from over-the-counter anti-inflammatories?

    Prescription naproxen is usually stronger and longer lasting than standard OTC anti-inflammatories. It may be preferred when shorter-acting medicines such as ibuprofen are not effective enough.

  • Can I buy naproxen online in the UK?

    Yes. You can buy naproxen online after completing a clinical assessment. A prescriber will check your symptoms, medical history and medicines before approving treatment.

  • Can naproxen help with period pain?

    Naproxen is often recommended for moderate or severe period pain because it reduces prostaglandins, the chemicals that trigger cramping. Starting treatment at the first sign of discomfort usually offers the best benefit. It may work better than standard painkillers for some people.

  • Should I take naproxen with food?

    Yes. Taking naproxen with food or milk helps protect the stomach lining and reduces the chance of indigestion. Regularly taking it on an empty stomach increases the risk of irritation, discomfort and long-term stomach problems.

  • Can I drink alcohol while taking naproxen?

    Light alcohol intake is usually safe, but drinking larger amounts increases the chance of stomach irritation, heartburn and dizziness. If you notice any stomach discomfort while taking naproxen, it is best to avoid alcohol entirely.

  • What should I do if naproxen does not help my pain?

    If naproxen is not easing your symptoms, you may need a different type of anti-inflammatory, a short course of another medicine or a change in dose under supervision. Adding paracetamol can help for some types of pain. A clinician can review the best next step.

  • Can naproxen affect my stomach or kidneys?

    Naproxen can irritate the stomach and may affect kidney function if used at high doses or for long periods. Staying hydrated and taking it with food reduces these risks. People with kidney disease or high blood pressure need extra caution.

  • How long is it safe to take naproxen for?

    Naproxen is usually taken short term, but some conditions require longer use under monitoring. If used for more than a few weeks, you may need checks for blood pressure, kidney function or stomach problems. Always use the lowest effective dose.

  • Can naproxen be used with topical gels or heat therapy?

    Yes. Using naproxen with topical gels, heat pads or cold packs can provide stronger relief for muscle and joint pain. Avoid using multiple anti-inflammatory gels at the same time to prevent irritation.

Related Treatments for Pain