• Effectively reduces bumps, pustules, and facial redness
  • Calms inflammation and soothes stinging or burning sensations
  • Delivers visible improvement in as little as 4–8 weeks with regular use

How it works?

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Overview

If rosacea flare-ups are leaving your skin red, sore, and difficult to manage, Metrogel is a trusted prescription treatment designed to restore calm. Containing metronidazole 0.75%, it works deep within the skin to reduce inflammation, ease redness, and shrink rosacea-related bumps — helping you feel more comfortable and confident in your skin.

Lightweight and easy to apply, Metrogel has been a first-line rosacea treatment for decades, offering reliable relief and long-term management of symptoms. For many, it’s the treatment that helps turn unpredictable flare-ups into something far more manageable.

This medicine requires a secure online consultation with a UK-registered prescriber, and will only be supplied if clinically appropriate.


What is Metrogel


Metrogel contains metronidazole 0.75%, a topical antibiotic and anti-inflammatory that has been widely prescribed for rosacea for decades. It is particularly effective for treating inflammatory papules, pustules, and persistent facial redness. By targeting bacteria on the skin and reducing inflammation, Metrogel helps calm the visible symptoms of rosacea while easing discomfort such as burning or stinging sensations.

The gel is applied directly to affected areas and is generally well tolerated with minimal risk of systemic absorption. With consistent use, many patients begin to notice an improvement in flare-ups within 4 to 8 weeks, with further progress seen over time. Metrogel is especially useful for those seeking a long-standing, evidence-based option to manage mild to moderate rosacea.

Directions

  • Apply a thin layer of Metrogel to the affected skin once or twice daily, as directed by your prescriber.
  • Gently cleanse and dry the skin before applying.
  • Avoid contact with eyes, mouth, or broken skin.
  • Continue treatment for the full course, as rosacea management often requires ongoing use.

Side Effects

Most people tolerate Metrogel well, but some may experience mild, temporary skin reactions — especially during the first few weeks of use.

Common (may affect up to 1 in 10 people):

•Redness or irritation where the gel is applied
• Dryness or a mild burning sensation
• Itching or stinging of the skin

These effects usually improve as your skin adapts to the treatment. If symptoms persist or become uncomfortable, stop using the gel and speak to your prescriber.

Disclaimer: This is not a full list of side effects. Always read the patient information leaflet provided with your medicine. If you experience anything unusual or worrying, contact a healthcare professional. In an emergency, call 999 or visit A&E.

Warnings

Do not use Metrogel if you:

  • Are allergic to metronidazole or any ingredients in the gel
  • Have open wounds or severely sensitive skin at the site of application


Other precautions:

  • Use daily sun protection, as rosacea skin is UV-sensitive
  • Safe for long-term use if prescribed, but consult your prescriber if pregnant or breastfeeding
Frequently asked questions

  • What is Metrogel and how does it work?

    Metrogel (metronidazole) is a topical anti-inflammatory antibiotic used to treat rosacea. It reduces the redness, bumps and irritation linked to flare-ups by calming inflammatory reactions in the skin. With consistent use, many people notice clearer, less reactive skin over time.

  • How do I apply Metrogel properly?

    Apply a thin layer of Metrogel (metronidazole) once or twice daily to clean, dry skin as directed by your clinician. Avoid the eyes and mouth, and allow the gel to absorb fully before using moisturiser, makeup or sunscreen. A simple, gentle routine helps reduce irritation while the treatment works.

  • How long does Metrogel take to show results?

    Most people begin noticing improvements after 3–6 weeks, with redness and papules continuing to settle over several months. Rosacea treatments work gradually, so it’s important to apply Metrogel consistently even if your skin appears unchanged in the early stages.

  • What symptoms does Metrogel help with?

    Metrogel (metronidazole) helps reduce red, inflamed bumps and background skin redness. It is especially useful for papulopustular rosacea, where inflammation is the main issue. It does not treat visible blood vessels, but it often improves the overall appearance and comfort of the skin.

  • Is Metrogel suitable for long-term use?

    Yes. Metrogel is widely used long term when rosacea is persistent or recurrent. Many people use it for several months at a time, with regular reviews to ensure the treatment continues meeting their needs without irritation.

  • Who should avoid using Metrogel?

    Metrogel shouldn’t be used by anyone allergic to metronidazole or other ingredients in the product. Tell a clinician if you have very sensitive or damaged skin, or if you’ve reacted to other topical treatments in the past.

  • Can I use Metrogel with moisturisers or makeup?

    Yes. You can safely use moisturisers, SPF and makeup over Metrogel (metronidazole) once it has fully absorbed. Many people find that gentle products and daily sunscreen support better results and help minimise irritation from environmental triggers.

  • Can Metrogel help with rosacea bumps that resemble acne?

    Yes. Metrogel (metronidazole) is specifically designed to treat inflammatory bumps caused by rosacea. These bumps may resemble acne, but respond better to rosacea-targeted treatments like Metrogel rather than traditional acne products.

  • Can Metrogel reduce skin sensitivity or stinging?

    Metrogel may help reduce the inflammation behind stinging and sensitivity, but it does not directly treat flushing. A gentle skincare routine and trigger avoidance usually help alongside treatment. If sensitivity is severe, a clinician may suggest adjusting how often you apply it.

  • Does Metrogel work for all types of rosacea?

    Metrogel (metronidazole) is most effective for papulopustular rosacea with bumps and redness. It is less effective for flushing or visible blood vessels. If your symptoms include these concerns, additional or alternative treatments may be more suitable.

  • Can Metrogel make my skin drier or irritated at first?

    Some people experience mild dryness or tightness in the first couple of weeks. This usually settles as the skin adjusts. Using a gentle moisturiser and applying Metrogel once daily initially can help minimise discomfort.

  • Can I combine Metrogel with other rosacea medicines?

    Yes. Metrogel is often used alongside treatments such as ivermectin, azelaic acid or brimonidine when symptoms need additional control. Combination therapy often gives stronger results, but it’s important to follow a clinician’s guidance to avoid irritation.

  • Will Metrogel help with redness that flares in hot weather or after alcohol?

    Metrogel doesn’t directly prevent flushing triggers such as heat, spicy foods or alcohol. However, by reducing underlying inflammation, some people notice overall redness becomes easier to manage. Lifestyle adjustments alongside treatment usually give better results.

  • What should I do if Metrogel stops working as well over time?

    If results slow down, a clinician may review your routine, adjust the application schedule or switch you to another treatment such as ivermectin or azelaic acid. Rosacea often changes over time, so periodic reviews are helpful.

  • Can I use Metrogel during a rosacea flare-up?

    Yes. Metrogel (metronidazole) can be continued during flare-ups, as it helps calm inflammation and reduce papules. If your skin feels very irritated, you may benefit from applying a thin layer less frequently for a few days while maintaining gentle skincare.

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