• Kills scabies mites and eggs fast
  • Quickly relieves itching and irritation
  • Trusted UK scabies treatment

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Overview

Dealing with scabies can be frustrating, uncomfortable, and disruptive - but the good news is, it’s easily treatable. Lyclear Cream (Permethrin 5%) is a trusted, prescription-strength treatment that kills the mites and eggs responsible for scabies in a single course.
It works deep within the skin to eliminate the infestation, relieve intense itching, and prevent reinfection when used correctly.

Fast, effective, and safe for adults and children over two months old, Lyclear is the first-line treatment recommended by UK guidelines for scabies.

This medicine requires a secure online consultation with a UK-registered prescriber and will only be supplied if clinically appropriate.


What is Permethrin 5% Cream


Permethrin 5% Cream contains the active ingredient permethrin, a type of medicine known as a pyrethroid. It works by paralysing and killing the scabies mites and their eggs, helping to clear the infection and relieve itching.

It’s used to treat:

  • Scabies (Sarcoptes scabiei) – a skin infestation causing intense itching and rash.
  • Crab lice (pubic lice) – occasionally prescribed when these infestations are resistant to other treatments.


Lyclear is highly effective because it:

  • Destroys mites and eggs in one or two applications.
  • Relieves itching and irritation as the infection clears.
  • Prevents reinfestation when household contacts are treated simultaneously.


Results are often visible within a few days, though itching may persist for up to 2–3 weeks as the skin recovers.

Directions

Always follow your prescriber’s instructions carefully.

  1. Apply to clean, cool, dry skin (not immediately after a hot bath or shower).
  2. Apply a thin layer over the entire body from the neck down, including under nails, soles of the feet, and between fingers and toes.
  3. In infants and elderly patients, also apply to the scalp, neck, face, and ears, avoiding the eyes and mouth.
  4. Leave on for 8-12 hours (overnight), then wash off thoroughly with soap and water.
  5. Reapply to hands if washed during the treatment period.
  6. Repeat after 7 days to kill any newly hatched mites.
  7. Wash bedding, clothing, and towels at 60°C, and vacuum furniture and carpets to prevent reinfection.


All close contacts and household members should be treated at the same time - even if they don’t have symptoms.

Side Effects

Most people tolerate permethrin well, and side effects are generally mild and temporary.

Common (may affect up to 1 in 10 people):

  • Mild burning or stinging after application
  • Itching or redness as the skin heals
  • Temporary tingling or numbness in treated areas


Less common (may affect up to 1 in 100 people):

  • Rash, irritation, or dryness
  • Exacerbation of existing eczema


Rare but serious (seek medical advice immediately):

  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Widespread redness or blistering


Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine. If you notice anything unusual or concerning, stop using the cream and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

Do not use Permethrin if you:

  • Are allergic to permethrin or any other pyrethroids.
  • Have open wounds or broken skin on the area to be treated.


Use with caution if you:

  • Have severe eczema (your prescriber may adjust application areas).
  • Are pregnant or breastfeeding - treatment can usually continue under medical supervision.


Avoid contact with eyes, mouth, and mucous membranes, and wash hands thoroughly after applying.
For external use only.

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