Permethrin 5% Cream is a first-line treatment for scabies. It works by paralysing and killing the mites and their eggs as they live on the skin’s surface. The cream must be applied to the entire body from the neck down to ensure full coverage, and a second application is usually required seven days later for complete eradication.

Apply Permethrin cream to clean, dry skin from the neck down, including between fingers and toes, under nails and around the groin area. Leave it on for 8-12 hours before washing off. Children and older adults may need application to the scalp too. A second dose after seven days is standard to kill newly hatched mites.

Permethrin begins working almost immediately against mites, but itching may continue for two to four weeks due to ongoing immune reactions in the skin. This does not mean the treatment has failed. If symptoms persist beyond four weeks, seek clinical advice for reassessment.

Yes. Everyone who lives with you or has prolonged close contact must be treated at the same time, even if they have no symptoms. Scabies spreads before itching begins, so coordinated treatment prevents reinfestation and improves success.

Permethrin is generally safe for children aged two months and over when used as directed. Infants may require application to the scalp and face, avoiding the eyes and mouth. Always follow medical guidance for young children to ensure correct dosing and application.

Temporary itching, redness, tingling or mild burning can occur as the skin reacts during treatment. These usually settle within days. Rarely, contact dermatitis or swelling can develop. If symptoms worsen or become severe, stop using the cream and seek medical advice.

Permethrin is often considered safe during pregnancy and breastfeeding, but treatment decisions should always be made with a clinician. They will confirm whether permethrin remains the best option or whether alternative products are suitable.

Yes. The standard regimen for Permethrin involves two applications spaced seven days apart. The first treatment kills live mites, while the second kills any newly hatched larvae. Skipping the second dose is a common cause of treatment failure and reinfestation within households.

Worsening itch can occur because the immune system continues reacting to dead mites in the skin. This is known as “post-scabetic itch” and does not mean the treatment has failed. Emollients or antihistamines may help, and symptoms typically reduce within several weeks.

Yes. Wash bedding, towels and clothing used in the previous three days at 60°C to kill mites. Items that cannot be washed can be sealed in a plastic bag for at least 72 hours. These cleaning steps help prevent reinfestation while treatment is ongoing.

Permethrin is generally tolerated by most skin types, but people with eczema or very sensitive skin may experience dryness or irritation. Using an emollient alongside treatment can help. If reactions become severe, seek advice for alternative treatments.

Yes. Permethrin and benzyl benzoate treat scabies through different mechanisms. People who do not tolerate one treatment can often use the other. A clinician can advise the best approach depending on your symptoms and treatment history.

Most people can return 24 hours after the first treatment because infectiousness begins to decline quickly. However, close contacts still require treatment and environmental measures should be followed to prevent ongoing spread.

Permethrin is also licensed for the treatment of head lice in lower strengths, but the 5% formulation is specifically for scabies. Always use the correct strength and product intended for the condition you are treating.

Failure is often due to missed areas during application, skipped second dosing, or untreated contacts. If permethrin is used correctly and symptoms persist beyond four weeks, your clinician may recommend benzyl benzoate or further evaluation for crusted scabies.