• Effectively treats conditions such as infected eczema, impetigo, and infected cuts or grazes
  • Targets the bacteria causing infection, helping skin to heal faster
  • Works directly on the infection

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Overview

Fusidic acid is a powerful topical antibiotic that targets bacterial skin infections at their source. Containing fusidic acid 2%, it works by stopping bacteria from multiplying, helping your skin heal while easing redness, soreness, and irritation.

Available as a cream (light, quick-absorbing) or ointment (richer, protective), Fusidic acid is often prescribed for infected eczema, dermatitis, or impetigo, giving your skin the chance to recover without further damage.

This treatment requires a secure online consultation with a UK-registered prescriber, and will only be supplied if clinically appropriate.


What is Fusidic acid


Fusidic acid is a topical antibiotic medicine that’s highly effective against Staphylococcus aureus — the bacteria most commonly linked with infected eczema and other skin conditions.

It’s usually prescribed for short courses (7–10 days) to treat:

  • Infected eczema or dermatitis patches
  • Impetigo (crusty, yellowish skin infection)
  • Infected cuts, grazes, or wounds
  • Other superficial bacterial skin infections


Unlike steroid creams, Fucidin does not reduce inflammation directly — instead, it clears infection, which then allows the skin to calm and heal naturally.

Directions

  • Apply a thin layer to the affected area three times daily, unless instructed otherwise.
  • Use sparingly — only enough to cover infected skin.
  • Wash hands before and after application.
  • Do not cover with airtight dressings unless advised by your prescriber.
  • Complete the full course, even if skin looks better sooner.

Side Effects

Like all medicines, Fusidic acid can cause side effects, although not everyone will experience them. Side effects are usually mild and temporary.

Common (may affect up to 1 in 10 people)

  • Temporary stinging or burning
  • Itching or mild irritation


Rare (may affect up to 1 in 1,000 people):

  • Rash or worsening of eczema
  • Signs of allergy such as redness, swelling, or blistering


Most people tolerate Fusidic acid well, and side effects (if they do occur) are usually mild. If you are concerned about any symptoms, or they do not improve, speak to your doctor, pharmacist, or prescriber.

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet provided with your medicine for full details. If you experience severe or worrying symptoms, seek medical advice straight away. In an emergency, call 999 or go to A&E.

Warnings

  • Do not use if allergic to fusidic acid or any ingredient in the cream/ointment.
  • Not suitable for viral or fungal skin infections (e.g. cold sores, athlete’s foot).
  • Avoid prolonged use — overuse may lead to antibiotic resistance.
  • Only use during pregnancy or breastfeeding if recommended by a prescriber.
Frequently asked questions
  • What is Fusidic Acid 2% Cream and how does it work?

    Fusidic Acid 2% Cream is a topical antibiotic used to treat mild to moderate bacterial skin infections, especially those caused by Staphylococcus bacteria. It works by stopping bacteria from multiplying, allowing the body to clear the infection more effectively. It is commonly used for impetigo, infected eczema and small infected wounds.

  • Which skin infections can Fusidic Acid treat?

    Fusidic acid is effective for conditions such as impetigo, infected eczema, folliculitis and small infected cuts or abrasions. It is generally suitable when symptoms are localised and mild. Larger, spreading or painful infections may require oral antibiotics instead.

  • How do I apply Fusidic Acid 2% Cream correctly?

    Apply a thin layer to the affected skin three to four times daily unless advised otherwise. Wash hands before and after use and avoid covering the area with tight dressings unless instructed. Treatment usually lasts 5-7 days. Stopping early may allow the infection to return

  • How long does Fusidic Acid take to work?

    Many people notice improvement within 1–2 days, with redness, soreness and crusting gradually settling. Full recovery often takes around a week. If the infection worsens, spreads or fails to improve after seven days, you should seek medical advice.

  • Can Fusidic Acid be used on infected eczema?

    Yes. Fusidic acid is commonly prescribed for infected eczema, especially when golden crusts or weeping develop. It treats the bacterial component while emollients continue to support the skin barrier. If significant inflammation is present, your clinician may recommend a combination antibiotic–steroid cream instead.

  • What are the common side effects of Fusidic Acid Cream?

    Most people tolerate fusidic acid well. Possible side effects include mild stinging, redness, itching or temporary irritation at the application site. Severe reactions such as swelling or blistering are uncommon. If irritation persists or spreads, stop using the cream and seek advice.

  • Can I use Fusidic Acid on my face?

    Yes, but with care. Fusidic acid can be used on facial infections such as impetigo or infected eczema when prescribed. Avoid the eyes and lips unless specifically directed. If you need treatment for eyelid or lip infections, your clinician may suggest alternatives like mupirocin.

  • Should Fusidic Acid be used with steroid creams?

    Fusidic acid alone treats the infection, but if inflammation, itching or eczema flare-ups are severe, a combination antibiotic–steroid cream such as Fucidin H or Fucibet may be more suitable. These reduce both infection and irritation in one treatment.

  • Can Fusidic Acid be used for fungal infections?

    No. Fusidic acid only treats bacterial infections and does not work on fungal conditions such as athlete’s foot, ringworm or yeast rashes. Using it incorrectly may delay proper treatment. Fungal infections respond better to creams like clotrimazole or terbinafine.

  • Can Fusidic Acid be used alongside oral antibiotics?

    Sometimes, yes. For more severe or spreading infections, clinicians may use fusidic acid cream alongside oral antibiotics to target surface bacteria while systemic treatment works deeper. This approach is usually reserved for worsening or persistent infections.

  • Is Fusidic Acid safe in pregnancy and breastfeeding?

    Fusidic acid is generally considered safe when used on small areas for short periods, but you should always check with a clinician before use. Avoid applying to the breast area while breastfeeding unless advised, as the medicine could transfer to your baby.

  • Can Fusidic Acid be used for boils or abscesses?

    Boils and abscesses often need drainage rather than topical antibiotics alone. Fusidic acid may help surrounding skin if infected, but it cannot penetrate deeply enough to treat the core of an abscess. If you suspect a boil, seek medical review.

  • Can Fusidic Acid be used inside the nose?

    Fusidic acid is not usually recommended for nasal use for infection control. If nasal carriage of Staphylococcus is suspected, mupirocin ointment is typically preferred as it is licensed for intranasal treatment.

  • What if Fusidic Acid doesn’t improve my infection?

    If symptoms are worsening, spreading, or not improving within seven days, the infection may be resistant, fungal, viral or deeper than topical antibiotics can reach. A clinician may switch you to mupirocin, a combination cream or oral antibiotics.

  • Can Fusidic Acid be used long term?

    No. Long-term use increases the risk of bacterial resistance, meaning the cream may stop working when you really need it. Courses should generally last no longer than 7–10 days. If infections keep returning, a clinician should assess the underlying cause.

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