• Contains antifungal, antibacterial, anti-inflammatory, and soothing agents in one formula
  • Relieves redness, itching, and irritation while treating underlying infection
  • Soothes and protects sore, inflamed skin

How it works?

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Overview

Timodine Cream is a unique all-in-one treatment designed to calm, protect, and heal sore, inflamed skin. Containing a carefully balanced mix of a mild steroid (hydrocortisone), antifungal (nystatin), antibacterial agent, and soothing zinc oxide, it provides fast relief from redness, itching, soreness, and infection.

It’s often prescribed for sweat rash, infected eczema, thrush-related irritation, and inflamed skin in delicate areas — restoring comfort while protecting the skin barrier.

This medicine requires a secure online consultation with a UK-registered prescriber, and will only be supplied if clinically appropriate.


What is Timodine


Timodine Cream is a trusted treatment where inflammation and infection overlap, particularly in skin folds or areas prone to moisture.

Key actions:

  • Hydrocortisone – reduces redness, itching, and irritation
  • Nystatin – clears yeast infections (including Candida/thrush)
  • Antibacterial agent – prevents secondary bacterial infection
  • Zinc oxide – protects, soothes, and promotes skin healing


Because of this combination, Timodine is particularly effective for conditions like:

  • Infected sweat rash (intertrigo)
  • Thrush-related skin irritation (e.g. under breasts, groin, between thighs)
  • Infected eczema or dermatitis patches
  • Nappy rash with infection
  • Sore, broken, or weeping skin in moist areas

Directions

  • Apply a thin layer to the affected skin 2–3 times daily, or as directed by your prescriber.
  • Use sparingly, just enough to cover the area.
  • Wash and dry skin gently before application.
  • Avoid covering with airtight dressings unless advised.
  • Do not use for longer than 7 days without medical supervision.
  • Store below 15° C.

Side Effects

Like all medicines, Timodine can cause side effects, although not everyone will experience them.

Common (may affect up to 1 in 10 people):

  • Temporary stinging, burning, or mild irritation
  • Skin dryness or flaking


Less common (may affect up to 1 in 100 people, more likely with prolonged or excessive use):

  • Thinning of the skin
  • Stretch marks
  • Worsening of untreated fungal or bacterial infections
  • Allergic reactions such as rash, swelling, or redness


Most people tolerate Timodine well, and side effects (if they do occur) are usually mild. If you are concerned about any symptoms, or they do not improve, speak to your doctor, pharmacist, or prescriber.

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet provided with your medicine for full details. If you experience severe or worrying symptoms, seek medical advice straight away. In an emergency, call 999 or go to A&E.

Warnings

  • Do not use if allergic to hydrocortisone, nystatin, or any ingredient.
  • Not suitable for untreated viral infections (e.g. cold sores, chickenpox).
  • Avoid prolonged use, especially on delicate areas, to prevent thinning of the skin.
  • Not recommended for facial use unless advised.
  • Use in pregnancy or breastfeeding only under prescriber supervision.
Frequently asked questions

  • What is Timodine Cream and what is it used for?

    Timodine Cream contains hydrocortisone, nystatin, benzalkonium chloride and dimeticone. It is used to treat sore, inflamed skin that has become infected with yeast or bacteria. It is commonly prescribed for irritant dermatitis, inflamed skin folds and infected nappy rash.

  • How does Timodine work?

    Timodine treats several issues at once. Hydrocortisone reduces redness and inflammation, nystatin targets yeast infections, benzalkonium chloride provides antibacterial action and dimeticone protects irritated skin. This makes it suitable for mixed infections or inflamed areas that need soothing and antimicrobial support.

  • How do I apply Timodine Cream correctly?

    Apply a thin layer to clean, dry skin two or three times daily unless advised otherwise. Avoid covering the area with tight dressings unless instructed. Wash hands before and after application and use only on the affected patches of skin.

  • How long should I use Timodine for?

    Timodine is typically used for short courses of 7-10 days. Prolonged use may lead to steroid-related skin changes or reduced effectiveness of the antifungal component. If symptoms do not improve within a week, speak to a clinician.

  • What skin conditions respond best to Timodine?

    Timodine is helpful for irritated skin folds, thrush-infected rashes, inflamed dermatitis and sore, moist areas that may harbour both yeast and bacteria. It is not for ringworm or athlete’s foot unless a clinician has advised it.

  • What are the common side effects of Timodine Cream?

    Some people notice mild burning, dryness or irritation after application. With long-term use, hydrocortisone can thin the skin or lighten pigmentation. If symptoms worsen, stop using the cream and seek medical advice.

  • Can Timodine be used on the face or groin?

    It may be used in skin folds or the groin if prescribed, but only for short periods because these areas absorb steroids more easily. Avoid using it on the face unless specifically advised.

  • Does Timodine help with thrush-related skin irritation?

    Yes. Timodine contains nystatin, which treats yeast infections on the skin. It is often prescribed for sore, red or moist areas in skin folds or nappy areas. If symptoms do not improve quickly, a clinician may suggest additional antifungal treatment. 

  • Can Timodine be used for infected nappy rash?

    Yes. Timodine is often used when nappy rash becomes inflamed and infected with yeast or bacteria. Apply thinly and for short periods only. If the rash worsens or blisters appear, seek medical advice promptly.

  • Can I use Timodine alongside emollients?

    Yes. Emollients protect the skin barrier and often speed up recovery. Apply Timodine first, allow it to absorb and use emollients between doses. Avoid applying thick emollient layers directly over Timodine.

  • Does Timodine treat athlete’s foot?

    No. Athlete’s foot usually needs a dedicated antifungal such as terbinafine or miconazole. Timodine is not recommended for this type of infection unless your clinician advises it for a mixed inflammation.

  • Can I use Timodine if I am pregnant or breastfeeding?

    Timodine may be used on small areas for short periods only if a clinician confirms it is safe. Avoid using it on or near the breasts during breastfeeding to prevent accidental transfer.

  • What should I do if Timodine irritates my skin?

    Mild stinging can happen when the skin is cracked or inflamed. If burning, redness or swelling increases, stop using the cream. You may need an alternative product such as a non-steroidal antifungal.

  • Can Timodine be used on broken or very moist skin?

    Timodine may be used on mildly broken or moist skin if prescribed, as the combination helps reduce infection and soothe inflammation. However, deeper wounds or open ulcers require different treatment.

  • Can Timodine be used if I am already using another steroid cream?

    You should not combine steroid creams without medical advice. Using multiple steroids increases the risk of side effects. Your clinician will decide whether Timodine alone meets your treatment needs.

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