• Dissolves in seconds without water
  • Works in as little as 30 minutes
  • Relieves pain, nausea and sensitivity together

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Overview

When migraines make swallowing difficult, relief should still be simple. Rizatriptan Oral Lyophilisate Tablets dissolve gently on your tongue, offering the same trusted migraine relief in a more convenient form. By calming brain signals and narrowing widened blood vessels, these melt-in-the-mouth tablets help ease pain, nausea, and light sensitivity quickly, so you can regain control without added stress.


At SwiftMedi, all orders are reviewed by a UK-registered prescriber following a secure online consultation, with discreet delivery direct to your door.


What are Rizatriptan Orodispersible Tablets


Rizatriptan Orodispersible Tablets are part of the triptan family of medicines (5-HT1 receptor agonists), designed specifically for the acute treatment of migraine attacks.

They work by:

  • Narrowing widened blood vessels in the brain
  • Calming overactive nerve pathways
  • Reducing migraine pain, nausea, and sensitivity to light or sound


The orodispersible form is particularly helpful for patients who:

  • Experience nausea or vomiting during attacks
  • Struggle to swallow standard tablets
  • Need fast, convenient migraine relief

Directions

  • Place one 10mg oral lyophilisate tablet on the tongue at the first sign of migraine.
  • The tablet will dissolve without the need for water.
  • If symptoms return, a second dose may be taken after 2 hours.
  • Do not take more than 2 doses in 24 hours.


Not suitable for children under 18. Always follow your prescriber’s instructions.

Side Effects

Like all medicines, Rizatriptan can cause side effects, although not everyone gets them. Most side effects are mild and resolve quickly.

Common (may affect up to 1 in 10 people):

  • Dizziness or drowsiness
  • Fatigue
  • Flushing or warmth in the face

 

Less common (may affect up to 1 in 100 people):

  • Dry mouth
  • Nausea or indigestion

 

Rare but serious (seek medical advice immediately):

  • Chest pain, pressure or tightness
  • Signs of a severe allergic reaction: swelling of the face, lips, tongue or throat, or difficulty breathing
  • Irregular heartbeat or palpitations

 

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine. If you notice anything unusual or concerning, stop using the medicine and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

Rizatriptan Oral Lyophilisate Tablets may not be suitable if you:

  • Are under 18 or over 65
  • Are pregnant or breastfeeding (unless advised)
  • Have heart disease, high blood pressure, or history of stroke
  • Are taking other triptans or ergotamine-based medicines
  • Are taking SSRIs or SNRIs (antidepressants) - risk of serotonin syndrome
  • Have severe liver or kidney disease


Always share your full medical history with your prescriber.

Frequently asked questions
  • What are rizatriptan 10mg orodispersible tablets and how do they work?

    Rizatriptan 10mg orodispersible tablets dissolve on the tongue and treat migraines by narrowing widened blood vessels and calming overactive pain pathways in the brain. They are useful when nausea or vomiting makes swallowing tablets difficult.

  • How do rizatriptan orodispersible tablets differ from standard rizatriptan tablets?

    Both forms contain the same active ingredient, but orodispersible tablets dissolve on the tongue without water. This can help when swallowing is difficult or when nausea slows digestion. The medical benefit is the same, but the melt format can feel quicker and easier to take.

  • How quickly do rizatriptan orodispersible tablets work?

    Many people notice relief within 20–30 minutes. Because the tablet dissolves in the mouth, it avoids delays caused by slow digestion during migraines. Taking it early in the migraine attack improves the chances of full relief and reduces the likelihood of recurrence.

  • How do I take rizatriptan orodispersible tablets correctly?

    Place the tablet on your tongue and allow it to dissolve fully before swallowing. No water is needed. Only take a second dose after the recommended interval and never exceed the daily maximum. If you frequently need repeat doses, ask about alternative triptans.

  • What side effects can rizatriptan orodispersible tablets cause?

    Common side effects include warm sensations, tingling, dizziness or tiredness. Some people notice slight throat or mouth discomfort as the tablet dissolves. Rare symptoms like severe chest pain or breathing difficulty require urgent medical attention. Persistent side effects may mean another triptan is better suited.

  • Who should not take rizatriptan orodispersible tablets?

    They are unsuitable for people with heart disease, previous stroke, certain rhythm problems, uncontrolled high blood pressure or severe liver disease. Some antidepressants may interact. A clinician will check your medical history before supply.

  • Are orodispersible tablets better if my migraines cause nausea or vomiting?

    Yes. Orodispersible tablets are ideal when swallowing is difficult or when vomiting occurs early in the migraine. They dissolve on the tongue and begin absorbing before reaching the stomach, so they often work more reliably for these types of attacks.

  • Do rizatriptan orodispersible tablets work faster because they dissolve in the mouth?

    Many people feel rapid relief because the tablet dissolves quickly and avoids delays caused by nausea or slow digestion. Although absorption still occurs mainly through the gut, the ease and speed of taking it often lead to a quicker onset of relief in practice.

  • Can I take rizatriptan orodispersible tablets without water if I am travelling or at work?

    Yes. The orodispersible format is ideal for travel, commuting or work environments where swallowing tablets or accessing water is difficult. It dissolves instantly, making it discreet, practical and convenient in busy settings.

  • Are rizatriptan orodispersible tablets helpful for people who get visual aura before pain starts?

    Yes. If taken during the aura phase, some people find attacks become milder or shorter. Taking the orodispersible tablet early can be easier for patients who struggle to swallow once symptoms escalate. Timing is key for best results.

  • Can I take anti-nausea medicine alongside rizatriptan orodispersible tablets?

    Yes. Many people safely combine them with anti-nausea medicines such as metoclopramide or prochlorperazine. This can improve absorption and comfort during attacks. Avoid opioid painkillers, as they increase the risk of medication-overuse headache.

  • What should I do if the orodispersible tablet dissolves too quickly or leaves a taste?

    This is normal. Letting it rest on the tongue without moving it too much can reduce aftertaste. The taste does not affect how well it works. If taste is a persistent issue, another formulation may be preferable.

  • Can rizatriptan orodispersible tablets help with waking migraines?

    Yes. Because they do not require water and begin working immediately, they are convenient for morning migraines when pain is already intense. Fast intake helps prevent the attack from building further.

  • How long do rizatriptan orodispersible tablets stay in the body?

    They work quickly but leave the body within several hours, similar to standard tablets. If migraines regularly return later in the day, a clinician may suggest a second dose after the recommended interval or an alternative triptan.

  • What should I do if the migraine returns after using an orodispersible tablet?

    You may be able to take a second dose after the safe interval. If symptoms keep returning, another triptan or a longer-acting option might be more effective. Keeping a diary can help identify patterns and triggers.