• Starts working within 30 minutes to visibly reduce redness
  • Results can last up to 12 hours with a single application
  • Ideal for patients where redness is the main or remaining concern

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Overview

If persistent facial redness from rosacea is leaving you feeling frustrated and self-conscious, Mirvaso offers targeted relief. This once-daily gel contains brimonidine 0.33%, which works by gently narrowing blood vessels in the skin to visibly reduce redness within hours — helping you face the day with greater confidence.

Unlike treatments that focus on bumps and inflammation, Mirvaso is designed specifically to tackle facial flushing and redness, providing fast and noticeable results that can last up to 12 hours.

This medicine requires a secure online consultation with a UK-registered prescriber, and will only be supplied if clinically appropriate.


What is Mirvaso


Mirvaso is a topical gel used to treat facial redness caused by rosacea

Its active ingredient, brimonidine tartrate 0.33%, works by narrowing the blood vessels just beneath the skin, reducing visible redness and flushing. This makes it particularly helpful for patients whose main symptom is persistent facial redness, even when other rosacea symptoms (like bumps or pustules) are under control.

Mirvaso typically begins working within 30 to 60 minutes, with results that may last up to 12 hours per application. It's not used to treat inflammatory spots or acne-like lesions - instead, it’s often prescribed as an add-on when redness remains the primary concern.

Directions

  • Apply a pea-sized amount of Mirvaso gel to each affected area (cheeks, nose, chin, forehead) once daily.
  • Wash hands before and after application.
  • Avoid eyes, lips, and inside of the nose or mouth.
  • Do not exceed the recommended dose, as overuse may worsen redness.

Side Effects

Mirvaso is generally well tolerated and effects usually improve with continued use or dose adjustment, but some users may experience:

Common (may affect up to 1 in 10 people):
• Temporary redness, burning, or irritation at the application site
• Flushing or warmth in the treated area

Less common (may affect up to 1 in 100 people):
• Dry skin or mild itching
• Headache

Rare but serious (seek medical advice promptly):
• Worsening of rosacea symptoms (more redness or flare-ups)
• Severe allergic reaction (swelling, rash, difficulty breathing)

 Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine for full details. If you notice anything unusual or concerning, stop using the gel and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

Do not use Mirvaso if you:

  • Are allergic to brimonidine or any ingredient in the gel
  • Have very sensitive skin prone to severe irritation


Other cautions:

  • Use sparingly and exactly as directed — more is not better
  • Discuss with your prescriber if you have cardiovascular problems, depression, or are taking blood pressure medication
  • Not recommended during pregnancy or breastfeeding unless advised by your doctor
Frequently asked questions

  • What is Mirvaso and how does it work?

    Mirvaso (brimonidine) is a gel used to reduce facial redness caused by rosacea. It works by tightening small blood vessels in the skin, which helps lessen flushing and visible redness for several hours after application. Most people notice a quick improvement shortly after use.

  • How quickly does Mirvaso start working and how long does it last?

    Mirvaso (brimonidine) usually starts working within 30 minutes. Its redness-reducing effects often last for up to 12 hours, although this can vary between individuals. Applying it once daily at the same time helps maintain steady results throughout the day.

  • How do I apply Mirvaso correctly?

    Apply a small pea-sized amount of Mirvaso (brimonidine) once daily to each affected area, spreading it gently and evenly over the face. Use only on intact skin and avoid the eyes and mouth. Allow it to absorb fully before applying moisturiser, makeup or sunscreen.

  • Can Mirvaso help with bumps and breakouts?

    No. Mirvaso (brimonidine) specifically targets redness and flushing, not the bumps or spots seen in papulopustular rosacea. If you have both redness and breakouts, your clinician may suggest combining Mirvaso with another treatment.

  • Is Mirvaso safe for daily or long-term use?

    Yes. Mirvaso (brimonidine) can be used daily for long-term redness control, provided you follow a clinician’s guidance. Most people tolerate it well, but dose adjustments may help if sensitivity or rebound redness develops. Regular reviews ensure it continues to suit your skin.

  • Who should avoid using Mirvaso?

    Mirvaso should not be used by anyone allergic to brimonidine or when the skin is broken, infected or severely irritated. Tell your clinician if you have sensitive skin, severe flushing episodes or eye conditions that require similar medicines.

  • Can I use moisturisers or makeup after applying Mirvaso?

    Yes. You can apply moisturiser, sunscreen or makeup after Mirvaso (brimonidine) has fully absorbed. A gentle skincare routine helps maintain results and supports the skin barrier, which is often more sensitive in rosacea.

  • Can Mirvaso cause rebound redness and how can I avoid it?

    Some people experience redness that returns more strongly after Mirvaso (brimonidine) wears off. This is usually managed by applying a smaller amount, using it less frequently or pairing it with a gentle skincare routine. A clinician can help adjust your regimen if this occurs.

  • Can Mirvaso help with redness triggered by heat or exercise?

    Mirvaso can help reduce baseline facial redness, but flushing triggered by heat, exercise or stress may still occur. Many people find symptoms more manageable with daily treatment, but avoiding known triggers remains important for best results.

  • Can I use Mirvaso alongside other rosacea gels or creams?

    Yes. Mirvaso (brimonidine) can be safely combined with treatments such as ivermectin, azelaic acid or metronidazole when redness and bumps occur together. Apply Mirvaso first, allow it to absorb, then apply other prescribed products.

  • Can Mirvaso worsen flushing for some people?

    A small number of people experience increased flushing or warmth after applying Mirvaso. This is usually managed by reducing the amount applied or using it every other day. If symptoms continue, your clinician may suggest switching treatment.

  • Will Mirvaso help visible blood vessels or thread veins?

    Mirvaso (brimonidine) reduces redness caused by dilated blood vessels, but it cannot remove fixed, visible thread veins. These usually require laser treatment. However, Mirvaso may still improve overall facial tone and reduce background redness.

  • Can Mirvaso be used during flare-ups or sensitive skin days?

    Yes, but use caution. If your skin feels very irritated, applying a small amount or spacing out applications may help prevent stinging. Gentle skincare alongside Mirvaso (brimonidine) often improves comfort during flare-ups.

  • Can Mirvaso be used with sunscreen or in sunny weather?

    Yes. Apply Mirvaso first, let it absorb, then use a high-SPF sunscreen. Sun exposure is a common rosacea trigger, so daily SPF use often enhances overall results and reduces flare-ups.

  • What should I do if Mirvaso stops working as well over time?

    If redness control becomes less effective, a clinican may review your routine, adjust application amounts or suggest combining Mirvaso (brimonidine) with other treatments that target inflammation or bumps. Rosacea often changes over time, so treatment plans may need updating.

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