• Targets bacteria linked to rosacea flare-up
  • Calms inflammation, reducing redness and visible bumps
  • Clinically proven treatment with decades of safe use

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Overview

If facial redness, bumps, and flare-ups from rosacea are affecting your confidence, Rozex is a trusted prescription treatment designed to calm and control symptoms. Containing metronidazole 0.75%, Rozex works directly on inflamed skin to reduce redness, shrink spots, and soothe irritation — helping you regain comfort and confidence in your complexion.

Gentle enough for long-term use, Rozex is a mainstay rosacea treatment worldwide. Applied once or twice daily, it works beneath the surface to bring flare-ups under control and support clearer, healthier-looking skin.

This medicine requires a secure online consultation with a UK-registered prescriber, and will only be supplied if clinically appropriate.


What is Rozex Gel


Rozex Gel (metronidazole 0.75%) is a well-established topical treatment for rosacea, combining antibacterial and anti-inflammatory action to relieve key symptoms.

It works by reducing inflammation, calming redness, and targeting microorganisms thought to worsen rosacea flare-ups. This makes it especially effective for managing the red bumps (papules), pustules, and irritation often associated with the condition.

Rozex is commonly prescribed for people experiencing:

  • Persistent facial redness and flushing
  • Papules and pustules linked to inflammatory rosacea
  • Burning, stinging, or increased skin sensitivity


With regular use, most patients notice visible improvement within 4–8 weeks, especially when used as part of a consistent skincare routine.

Directions

  • Apply a thin layer of Rozex gel or cream to affected skin once or twice daily, as directed by your prescriber.
  • Wash and gently dry the skin before application.
  • Avoid contact with eyes, mouth, and broken skin.
  • Treatment courses typically last several weeks to months for best results.

Side Effects

Rozex is generally well tolerated, but some people may experience mild skin reactions, especially during the first few weeks of treatment.

Common (may affect up to 1 in 10 people):

  • Redness, dryness, or irritation at the site of application
  • Itching or a mild burning or stinging sensation


Less common: (may affect up to 1 in 100 people)

  • Skin sensitivity or peeling
  • Unusual skin reactions such as tingling


Rare but serious (stop use and seek medical advice):

  • Signs of an allergic reaction such as rash, swelling, or difficulty breathing


Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine. If you notice anything unusual or your symptoms worsen, stop using the product and contact your prescriber. In an emergency, call 999 or visit A&E.

Warnings

Do not use Rozex if you:

  • Are allergic to metronidazole or any ingredients in the gel/cream
  • Have very sensitive or broken skin at the site of application


Other cautions:

  • Avoid excessive sun exposure or tanning beds during use
  • Safe for long-term treatment if prescribed, but check suitability if pregnant or breastfeeding
Frequently asked questions

  • What is Rozex Gel and how does it work?

    Rozex Gel (metronidazole) is a topical antibiotic used to treat rosacea. It works by reducing inflammation and calming the small bumps and redness linked to flare-ups. With consistent use, many people notice their skin becoming clearer and less irritated.

  • How should I apply Rozex Gel?

    Apply a thin layer of Rozex Gel (metronidazole) once or twice daily to clean, dry skin, unless your clinician advises otherwise. Avoid the eyes and mouth, and allow it to absorb before using moisturiser or sunscreen. Keeping your routine simple and gentle helps reduce irritation.

  • How long does Rozex Gel take to start working?

    Rozex Gel usually begins improving redness and bumps after 3–6 weeks, with clearer skin continuing over several months. Rosacea treatments work gradually, so it’s important to apply it consistently even if your skin does not improve straight away.

  • What symptoms does Rozex Gel help with?

    Rozex (metronidazole) helps reduce inflammatory bumps, papules and background redness caused by rosacea. While it won’t treat visible blood vessels, it often helps the overall skin tone appear calmer and less reactive.

  • Is Rozex Gel safe for long-term use?

    Yes. Rozex Gel is commonly used long term when rosacea is persistent. Many people continue treatment for months to maintain clearer skin, with periodic reviews to check it remains suitable.

  • Who should avoid using Rozex Gel?

    Avoid Rozex Gel if you have an allergy to metronidazole or other ingredients in the product. Tell a clinician if your skin is extremely sensitive, broken or sunburnt before starting treatment, as you may need a slower introduction.

  • Can I use Rozex Gel with moisturisers, sunscreen or makeup?

    Yes. Allow Rozex Gel (metronidazole) to fully absorb before applying your moisturiser, SPF or makeup. A gentle routine and daily sunscreen often help prevent flare-ups and support smoother results.

  • Does Rozex Gel help with flushing or burning sensations?

    Rozex Gel (metronidazole) can help calm background redness, but flushing and burning sensations often respond better to trigger control or other medical treatments such as brimonidine gel. Many people use Rozex alongside lifestyle changes to reduce these symptoms.

  • Can Rozex Gel improve acne-like breakouts linked to rosacea?

    Yes. Rozex effectively targets the inflammatory bumps that look similar to acne but are caused by rosacea. By reducing swelling and calming the skin, these breakouts often become less frequent and less noticeable over time.

  • Can Rozex Gel make my skin worse before it gets better?

    Some people notice mild dryness, tightness or irritation during the first couple of weeks of Rozex use. This usually settles as the skin adjusts. If irritation becomes persistent, reducing application frequency and using a simple moisturiser can help.

  • Can I use Rozex Gel with other rosacea treatments?

    Rozex Gel is often combined with other treatments such as azelaic acid or ivermectin when symptoms are more stubborn. Using a combination can improve results, but it’s important to follow a clinician’s plan so the skin is not overloaded.

  • Will Rozex Gel help if my main issue is visible veins?

    Rozex Gel helps reduce inflammatory symptoms, but it does not remove visible blood vessels (telangiectasia). These usually require laser therapy or specialist treatment.Rozex may still help the overall redness look milder.

  • Can Rozex Gel be used around the nose or sensitive areas?

    Yes, but apply it carefully. Rozex (metronidazole) can be used around the nose where rosacea often flares, but avoid getting it inside the nostrils. If sensitivity occurs, use a smaller amount or apply moisturiser first.

  • What should I do if Rozex Gel isn’t helping my symptoms?

    Some people need a combination of treatments or a switch to alternatives like ivermectin or azelaic acid if Rozex alone isn’t enough. Reviewing lifestyle triggers can also improve results. A clinician can guide your next steps.

  • Does Rozex Gel help prevent future rosacea flare-ups?

    Consistent use of Rozex Gel (metronidazole) can help reduce the frequency of flare-ups by managing underlying inflammation. Combining treatment with good skincare and trigger avoidance usually provides the best long-term control.

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