• Dual-action Clotrimazole pack for full thrush treatment
  • Relieves internal infection and external irritation together
  • Trusted Canesten brand with fast, effective results

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Overview

Canesten Combi is a complete thrush treatment that clears the infection from the inside while soothing irritation on the outside.
It combines a clotrimazole vaginal pessary with a 2% clotrimazole cream, giving fast and effective relief from all symptoms of vaginal thrush.


What is Canesten Combi


Thrush often causes both internal infection (discharge, soreness, swelling) and external discomfort (itching, burning, redness). Treating only one side can leave symptoms lingering, which is why Canesten Combi provides two treatments in one pack.

  • The vaginal pessary delivers antifungal medicine directly inside the vagina, targeting the Candida yeast responsible for thrush.
  • The external cream relieves itching, burning, and soreness around the vulva.


Together, they offer comprehensive relief - tackling both the infection and the discomfort it causes. Most women notice improvement in just a few days.

Directions

  • Insert the pessary into the vagina at bedtime using the applicator provided.
  • Apply the clotrimazole 2% cream thinly to the external area 2–3 times daily until symptoms settle.
  • Use both treatments together for best results.

Side Effects

Most women tolerate Canesten Combi well, but side effects may occur.

Common (may affect up to 1 in 10 people):

  • Mild burning, stinging, or irritation after application
  • Redness or itching


Less common (may affect up to 1 in 100 people):

  • Vaginal discomfort
  • Skin rash


Rare but serious (seek urgent advice):

  • Severe allergic reaction (swelling, rash, difficulty breathing)


Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine for full details. If you notice anything unusual or concerning, stop using the treatment and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

  • Not suitable if allergic to clotrimazole or other antifungals.
  • Avoid use during pregnancy unless advised by a doctor (pessary may be inserted without the applicator in pregnancy).
  • Cream may weaken latex condoms and diaphragms — use additional contraception during treatment.
  • If symptoms persist or recur, seek medical advice.
Frequently asked questions

  • What is Canesten Combi and what does it treat?

    Canesten Combi contains an internal thrush treatment (usually a vaginal pessary or internal cream) plus clotrimazole 2% External Cream. The internal treatment clears the yeast infection at its source, while the external cream relieves itching, redness and soreness around the vulva. It is used for uncomplicated vaginal thrush confirmed by typical symptoms.

  • How do I use Canesten Combi correctly?

    Insert the internal pessary or internal cream using the applicator before bedtime, allowing it to work overnight. Apply the clotrimazole External Cream two or three times daily to relieve itching and discomfort. Continue using the external cream for several days even once symptoms start improving.

  • How quickly does Canesten Combi work?

    Many women experience relief from itching within a few hours of applying the external cream, while the internal treatment usually improves symptoms within 24 to 48 hours. Full resolution can take two to three days. Seek help if symptoms persist beyond one week.

  • Is Canesten Combi better than a pessary or cream alone?

    Yes. The internal treatment clears the infection while the external cream provides fast symptom relief. Using only an internal pessary may leave ongoing irritation, and using only an external cream will not treat internal thrush. The combination approach improves comfort and treatment completeness.

  • Who should not use Canesten Combi?

    Avoid Canesten Combi if you are pregnant, have unexplained bleeding, irregular discharge, fever, abdominal pain or are allergic to clotrimazole. Women with their first episode of symptoms should consider medical assessment to confirm thrush before use.

  • What side effects can occur with Canesten Combi?

    Mild burning, redness or irritation can occur during application of clotrimazole cream. The internal treatment may cause temporary soreness or increased discharge as the pessary dissolves. These effects are usually short-lived, but stop use if irritation becomes severe.

  • Does Canesten Combi treat both internal and external thrush symptoms?

    Yes. The internal pessary or internal cream treats the yeast infection inside the vagina, while the external cream soothes itching and redness on the surrounding skin. Using both together helps ensure the infection and symptoms settle completely.

  • Can I use Canesten Combi if I am on my period?

    The internal pessary or internal cream may be less effective during heavy bleeding as it can be washed out. It is usually recommended to delay treatment until after your period. The external cream can still be used for temporary symptom relief if discomfort is significant.

  • Does Canesten Combi interfere with condoms or diaphragms?

    Yes. Clotrimazole External Cream can weaken latex condoms and diaphragms, reducing their reliability. Non-latex options or alternative contraception should be used during treatment. Wait until the cream is fully absorbed before using latex products again.

  • Will the internal pessary cause extra discharge?

    Yes. The pessary melts inside the vagina, producing a white, chalky discharge that can be mistaken for worsening thrush. This is normal and simply indicates the pessary is dissolving. Wearing a panty liner can help with comfort overnight.

  • Can I use Canesten Combi if I’m also experiencing external irritation from shaving or sweating?

    Yes. The clotrimazole cream can help relieve soreness from shaving, sweating or friction alongside treating fungal irritation. However, if irritation persists independently of thrush symptoms, consider stopping the cream and seeking advice to rule out dermatitis.

  • Can I still exercise or swim while using Canesten Combi?

    You can stay active, but swimming, cycling or exercise causing friction may increase local irritation while the pessary is dissolving. Many women find it more comfortable to avoid intense activity for the first 24 hours.

  • Does Canesten Combi work for persistent itching even after the infection clears?

    The external cream can help settle lingering irritation while the skin heals. Persistent itching after treatment may suggest sensitivity, dermatitis or another condition, so speak with a clinician if symptoms continue.

  • Can I use Canesten Combi after antibiotics?

    Yes. Antibiotics commonly trigger thrush by disrupting natural vaginal flora. Using both the internal and external treatments in Canesten Combi helps manage infection and soothe irritation caused by antibiotic-related thrush.

  • What should I do if symptoms return soon after finishing Canesten Combi?

    You may need a second internal dose or an alternative treatment such as fluconazole, especially if symptoms recur quickly. Frequent infections may indicate triggers or an underlying cause, so a clinician can help plan ongoing management.

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