• The most prescribed single-dose capsule for thrush
  • Works fast - relief often within 24-48 hours
  • Convenient oral treatment - no creams or pessaries needed

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Overview

Fluconazole 150mg is a simple, single-dose capsule that clears vaginal thrush fast.
Just one tablet targets the yeast infection from within, easing itching, discharge, and discomfort - with most women noticing improvement in as little as 24 hours.


What is Fluconazole 


Vaginal thrush is caused by an overgrowth of the yeast Candida albicans, leading to itching, soreness, swelling, and thick white discharge. Fluconazole 150mg works by stopping the yeast from multiplying, allowing your body to restore its natural balance.

Unlike creams or pessaries, fluconazole is an oral treatment - meaning it works throughout the body, making it particularly helpful for women who prefer a discreet, no-fuss option or who have recurrent infections.

Single capsule course - convenient and easy to take


Fast-acting - many women feel relief within 24-48 hours


Effective - clears infection and reduces recurrence risk when taken correctly

Directions

  • Standard dose: One 150mg capsule, taken with water.
  • Can be taken with or without food.
  • Symptoms usually improve within 1–2 days.
  • Always complete the course - do not take extra unless directed by your prescriber.

Side Effects

Most people tolerate fluconazole well, but side effects can occur.

Common (may affect up to 1 in 10 people):

  • Headache
  • Stomach upset, nausea, or diarrhoea
  • Skin rash


Less common (may affect up to 1 in 100 people):

  • Dizziness
  • Changes in liver function tests (rarely cause symptoms)


Rare but serious (seek urgent medical advice):

  • Severe allergic reaction (swelling, rash, breathing difficulty)
  • Yellowing of skin/eyes (possible liver problem)
  • Irregular heartbeat


Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine for full details. If you notice anything unusual or concerning, stop taking fluconazole and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

  • Not suitable if allergic to fluconazole or other azole antifungals.
  • Avoid if pregnant or breastfeeding unless prescribed by a doctor.
  • Use with caution if you have liver or kidney disease.
  • Can interact with some medicines (including warfarin and statins) — always disclose other treatments to your prescriber.
Frequently asked questions
  • What is fluconazole 150mg and how does it work for thrush?

    Fluconazole 150mg is an antifungal capsule used to treat vaginal thrush. It works by stopping Candida yeast from growing, helping symptoms settle within a few days. Many women prefer it because one capsule is often enough for uncomplicated cases.

  • How quickly does fluconazole start working?

    Most people notice improvement within 24 to 48 hours, although itching may ease sooner. Full recovery usually takes a few days. If symptoms persist for more than a week, you may need an alternative antifungal or a review to confirm the diagnosis.

  • Is one fluconazole capsule enough to treat thrush?

    For most uncomplicated thrush episodes, one 150mg capsule is enough. If symptoms are severe, return quickly or persist, a clinician may advise a second dose after 72 hours. Recurrent thrush may require a longer treatment plan.

  • Can I use fluconazole and a thrush cream together?

    Yes. Many women use fluconazole alongside an external antifungal cream to quickly relieve itching or burning. This combination can help settle both internal and external symptoms more comfortably.

  • Who should not take fluconazole?

    Fluconazole is not suitable if you are pregnant, breastfeeding, allergic to azole antifungals, or taking certain medicines such as quinidine or amiodarone. Always check with a clinician if you have liver problems or take regular medication.

  • What are the common side effects of fluconazole?

    Most people tolerate fluconazole well. Possible side effects include headache, stomach upset, nausea or diarrhoea. Serious reactions are rare but require urgent attention. If symptoms worsen or new symptoms appear, seek medical advice.

  • Can I take fluconazole if it’s my first time having thrush?

    If symptoms are typical of thrush, fluconazole can be used, but first-time episodes often benefit from medical confirmation. This helps rule out conditions that may mimic thrush, such as BV or irritation from products.

  • Can fluconazole treat thrush caused by antibiotics?

    Yes. Antibiotics often trigger thrush by disturbing natural bacteria, allowing yeast to overgrow. Fluconazole can effectively clear symptoms, though you may also benefit from avoiding perfumed products and using gentle skincare until the irritation settles.

  • Can fluconazole help with recurrent thrush?

    It can, but recurrent thrush may need a structured treatment plan rather than single-dose capsules. Clinicians sometimes prescribe fluconazole weekly for several months. Identifying triggers like hormones, antibiotics or tight clothing is also important.

  • Can I take fluconazole during my period?

    Yes. Fluconazole works just as well during your period. However, some women still choose to use a cream at the same time if itching or soreness worsens around menstruation.

  • Does fluconazole interact with alcohol?

    Alcohol does not directly affect how fluconazole works, but both can irritate the stomach or cause nausea in some people. If you feel unwell, limit alcohol until symptoms settle.

  • Can men take fluconazole for thrush?

    Yes. Fluconazole can treat fungal infections in men, including penile thrush. Men with recurrent symptoms should seek medical advice to check for underlying causes such as diabetes or irritation.

  • Is fluconazole suitable if I also have BV symptoms?

    No. Fluconazole only treats yeast infections, not bacterial vaginosis. If you have discharge with a noticeable odour or thin, watery texture, a different treatment is needed. A clinician can help distinguish between the two.

  • Can fluconazole cause discharge changes while working?

    Some women notice temporary changes in discharge as yeast levels fall. This usually settles within a few days. If discharge becomes unusually coloured, smelly or blood-stained, another condition may be present and you should seek advice.

  • What should I do if fluconazole doesn’t work?

    If symptoms do not improve within seven days, you may need a second dose, an internal pessary or a review to confirm the diagnosis. Persistent or unusual symptoms should always be checked by a clinician.

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