• Powerful relief for stubborn eczema, psoriasis, and dermatitis
  • A potent steroid for short-term, resistant flare-ups
  • Versatile cream, ointment, and scalp application formats

How it works?

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Overview

When nothing else works, Dermovate is the strongest steroid cream and ointment available to tackle severe skin flare-ups head-on. Containing clobetasol propionate 0.05%, Dermovate is prescribed for stubborn eczema, psoriasis, and dermatitis that haven’t responded to weaker treatments.

Available as a cream (light, quick-absorbing) or ointment (rich, protective, hydrating), it delivers intensive anti-inflammatory action where it’s needed most.

Dermovate can only be supplied following a secure online consultation with a UK-registered prescriber, and will only be provided if clinically appropriate.


What is Dermovate


Dermovate is classed as a very potent corticosteroid — the highest strength in its category. It works by powerfully reducing inflammation in the skin, calming redness, itching, and scaling that cause so much distress during flare-ups.

Because of its potency, Dermovate is reserved for short-term use when other treatments (like Hydrocortisone, Eumovate, or Betnovate) have failed to bring the condition under control.

Conditions commonly treated with Dermovate include:

  • Severe eczema and dermatitis
  • Psoriasis (localised, resistant patches)
  • Lichen planus
  • Lupus erythematosus affecting the skin
  • Other inflammatory skin conditions unresponsive to weaker steroids

Directions

  • Apply a thin layer to affected areas once or twice daily, as directed by your prescriber.
  • Use the minimum amount needed to control symptoms.
  • Do not use on the face, groin, or underarms unless advised by a prescriber.
  • Treatment should usually not exceed 4 weeks without review.
  • Wash hands after applying unless treating the hands themselves.

Side Effects

Like all medicines, Dermovate can cause side effects, although not everyone will experience them. Because it is a very potent corticosteroid, the risk of side effects is higher if it is misused, used on sensitive areas, or applied for long periods.

Common (may affect up to 1 in 10 people, usually with short-term use):

  • Burning, stinging, or irritation
  • Dryness or itching at the application site


Less common (may affect up to 1 in 100 people, more likely with prolonged use):

  • Thinning of the skin
  • Stretch marks
  • Visible blood vessels
  • Skin colour changes
  • Worsening of untreated skin infections


Most people tolerate Dermovate well when used exactly as directed. If you are concerned about any symptoms, or they do not improve, speak to your doctor, pharmacist, or prescriber.

Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet provided with your medicine for full details. If you experience severe or worrying symptoms, seek medical advice straight away. In an emergency, call 999 or go to A&E.

Warnings

  • Not suitable if allergic to clobetasol or other corticosteroids.
  • Avoid use on untreated bacterial, fungal, or viral skin infections.
  • Not for long-term continuous use unless under specialist supervision.
  • Not usually recommended for children.
  • Pregnant or breastfeeding women should consult a prescriber before use.
Frequently asked questions

  • What is Dermovate Ointment and what is it used for?

    Dermovate Ointment (clobetasol propionate 0.05%) is an ultra-potent steroid used to treat severe eczema, psoriasis and dermatitis that have not improved with weaker treatments. Its thick, greasy base helps soften very dry or scaly patches while the steroid reduces inflammation quickly during short flares.

  • How does Dermovate Ointment differ from the cream?

    Dermovate Ointment is more occlusive than the cream, meaning it traps moisture and enhances steroid absorption. This makes it better for extremely dry, thickened or chronic areas, while the cream suits moist or inflamed patches. Both contain the same potent steroid but behave differently on the skin.

  • How should Dermovate Ointment be applied?

    Apply a thin layer once or twice daily using the fingertip-unit method. Because ointments spread slowly, warm the area slightly before applying. Wash hands afterwards and allow the medicine to absorb before using moisturisers. Use only as prescribed, as very strong steroids require caution.

  • What side effects can Dermovate Ointment cause?

    Possible side effects include stinging, burning or dryness. Long-term or incorrect use may cause thinning skin, visible blood vessels or stretch marks. Because ointments enhance absorption, they must be used carefully and only on areas recommended by a clinician.

  • Can I use Dermovate Ointment on my face?

    No. Dermovate Ointment should not be used on the face unless specifically directed by a clinician. Facial skin absorbs steroids more easily and is prone to irritation and thinning, so milder treatments are normally recommended.

  • How long can I use Dermovate Ointment for?

    Treatment is usually limited to a few days up to two weeks. Dermovate Ointment is not suitable for long-term or daily use due to its high potency. If symptoms return, a clinician may create a step-down plan to keep the condition controlled safely.

  • Is Dermovate Ointment good for psoriasis plaques?

    Yes. The ointment’s moisturising base softens thick plaques so the steroid can absorb more effectively. It is often used for short bursts on stubborn areas during severe psoriasis flares before stepping down to milder treatments.

  • Can Dermovate Ointment be used on cracked or very dry skin?

    Yes, but only if the area is not infected. The ointment’s occlusive base helps soften cracks and reduce discomfort, but weeping or crusted patches may need an antibacterial treatment instead.Seek advice if the skin does not improve.

  • Does Dermovate Ointment work better at night?

    Many people use Dermovate Ointment at night because it stays on the skin longer and provides sustained moisturising effects. Night use also reduces the greasy feel during the day. This can improve comfort in dry, thickened areas.

  • Can Dermovate Ointment be used under dressings?

    Do not use Dermovate Ointment under airtight dressings unless told to by a clinician. Occlusion greatly increases steroid absorption and raises the risk of side effects. For routine use, apply sparingly without covering.

  • Can Dermovate Ointment be combined with moisturisers?

    Yes. Apply Dermovate Ointment first, allow it to absorb, then apply moisturisers to support the skin barrier. This combination helps reduce dryness and improves flare control. Avoid applying emollients too soon as they may dilute the steroid.

  • Is Dermovate Ointment suitable for lichenified (thickened) eczema?

    Yes. Thickened areas often respond better to ointments because they soften the skin and improve steroid penetration. Dermovate Ointment is commonly used for short bursts on these stubborn patches.

  • Can Dermovate Ointment be used for hand or foot eczema?

    Yes. Hands and feet often need stronger steroids due to thicker skin. Dermovate Ointment can help calm severe flares, though treatment should still be short. Using moisturisers and avoiding irritants supports better long-term control.

  • Does Dermovate Ointment feel greasier than creams?

    Yes. Ointments contain more oils and no water, so they feel heavier and leave a shiny finish. This can be beneficial for dry patches but may be less comfortable for daytime use. Many people use the ointment at night and cream during the day.

  • Can Dermovate Ointment be used when stepping down from even stronger treatments?

    Yes. Dermovate Ointment is often part of a steroid step-down plan, helping control symptoms after using very potent or specialist treatments. It offers strong anti-inflammatory action while gradually reducing steroid exposure.