• Combines anti-inflammatory and anti-parasitic action to treat the root causes of rosacea
  • Targets Demodex mites, which may worsen rosacea in some people
  • Clinically proven to reduce redness and flare-ups within 2–4 weeks&

How it works?

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Overview

If rosacea flare-ups are leaving your skin irritated, red, and covered in stubborn bumps, Soolantra offers a fresh approach. This once-daily cream contains ivermectin 1%, a treatment that not only calms inflammation but also targets microscopic skin mites thought to play a role in rosacea — helping break the cycle of flare-ups at the source.

Gentle yet powerful, Soolantra is designed for everyday use and is proven to reduce papules and pustules, restore skin comfort, and give patients the confidence of clearer, calmer skin.

This medicine requires a secure online consultation with a UK-registered prescriber, and will only be supplied if clinically appropriate.


What is Soolantra


Soolantra is a once-daily topical treatment for rosacea that contains ivermectin 1%
It offers a dual approach to managing rosacea by combining:

  • Anti-inflammatory effects – helping reduce redness, swelling, and irritation
  • Anti-parasitic action – targeting Demodex mites, which may contribute to rosacea flare-ups


Soolantra is particularly effective for moderate to severe rosacea with inflammatory lesions (bumps and pustules). Visible improvement is often seen within 2–4 weeks, with further benefits over continued use.

Directions

  • Apply a thin layer of Soolantra cream once daily to the affected areas of the face.
  • Use on clean, dry skin.
  • Avoid eyes, lips, and inside the nose.
  • Wash hands before and after application.
  • Consistency is key — continued daily use helps maintain results.

Side Effects

Most people tolerate Soolantra well, but like all medicines, it can cause side effects in some individuals.

Common (may affect up to 1 in 10 people):

  • Mild skin dryness
  • Burning, stinging, or itching at the application site
  • Temporary irritation during the first few days of use


Uncommon (may affect up to 1 in 100 people):

  • Redness or worsening of rosacea
  • Skin sensitivity
  • Eye irritation (if applied too close to the eyes)


Disclaimer: This is not a complete list of side effects. Always read the patient information leaflet that comes with your medicine for full details. If you notice anything unusual or concerning, stop using the cream and seek medical advice promptly. In an emergency, call 999 or go to A&E.

Warnings

Do not use Soolantra if you:

  • Are allergic to ivermectin or any of the ingredients in the cream


Other cautions:

  • Only apply to the face — not suitable for body use
  • Safety during pregnancy and breastfeeding is not fully established, so consult your prescriber before use
  • Always use as directed; over-application will not improve results faster
Frequently asked questions

  • What is Soolantra and how does it work?

    Soolantra (ivermectin) is a topical cream used to treat rosacea, especially when bumps and inflammation are present. It works by reducing inflammatory reactions in the skin and targeting Demodex mites, which are often higher in people with rosacea. Many users notice clearer, calmer skin with regular application.

  • How long does Soolantra take to work?

    Most people start noticing improvements within 2–4 weeks, although full results often take 8–12 weeks. Soolantra (ivermectin) works gradually as inflammation settles and skin becomes less reactive. Using it consistently each day gives the best chance of achieving long-term control.

  • How do I apply Soolantra correctly?

    Apply a pea-sized amount of Soolantra (ivermectin) once daily to clean, dry skin. Spread a thin layer over affected areas, avoiding the eyes and mouth. Allow it to absorb fully before applying moisturiser or sunscreen. A gentle routine helps prevent irritation while supporting effectiveness.

  • What symptoms does Soolantra help with?

    Soolantra (ivermectin) is especially effective at treating inflammatory bumps, pustules and persistent irritation related to papulopustular rosacea. It is less effective for flushing or visible blood vessels, which may require alternative or additional treatment.

  • Is Soolantra safe for long-term use?

    Yes. Soolantra is often used for several months or longer when rosacea is persistent. Many people continue using it daily or several times a week to maintain control. Treatment plans should be reviewed periodically to ensure ongoing effectiveness and skin comfort.

  • Who should avoid Soolantra?

    Soolantra should not be used by anyone allergic to ivermectin or any ingredients in the cream. It may not be suitable for people with extremely sensitive or broken skin. Always inform your clinician about past reactions to topical treatments.

  • Can I use makeup or moisturiser with Soolantra?

    Yes. Moisturiser, sunscreen and makeup can be applied once Soolantra (ivermectin) has fully absorbed. Using gentle, fragrance-free products helps improve comfort and supports the skin barrier, which is often more reactive in rosacea.

  • Does Soolantra help with Demodex mites linked to rosacea?

    Yes. Soolantra (ivermectin) directly targets Demodex mites, which are often found in higher numbers on rosacea-affected skin. Reducing these mites can significantly improve inflammatory bumps and overall skin comfort. Not all treatments target mites, which is why Soolantra can be particularly effective for certain patients.

  • Can Soolantra reduce redness or flushing?

    Soolantra helps with redness caused by inflammation but does not treat flushing triggered by heat, stress or alcohol. If flushing is your main issue, your clinician may recommend a treatment like brimonidine for targeted redness control.

  • Can Soolantra be used alongside other rosacea medicines?

    Yes. Soolantra (ivermectin) is often combined with metronidazole, azelaic acid or brimonidine when multiple symptoms occur. Apply Soolantra first, let it absorb, then continue with other treatments as directed. Combination therapy often gives stronger overall control.

  • Will Soolantra make my skin peel or sting at first?

    Some people notice mild dryness, tightness or temporary irritation during the first couple of weeks. This usually settles as your skin adjusts. Using a gentle moisturiser alongside treatment often helps reduce discomfort.

  • Can I use Soolantra during a rosacea flare-up?

    Yes. Soolantra (ivermectin) can be continued during flare-ups because it helps calm inflammation. If your skin feels especially sensitive, you may reduce application frequency temporarily and rebuild as comfort improves.

  • Will Soolantra help with rough or thickened skin?

    Soolantra helps with bumps and inflammation, but it does not treat thickened skin caused by phymatous rosacea. Thickened areas usually require specialist treatments such as laser or dermatology review.

  • Can Soolantra help if my rosacea worsens with stress or weather changes?

    Soolantra (ivermectin) helps manage the inflammatory bumps linked to rosacea, but triggers like stress, sunlight or temperature changes may still cause flare-ups. Combining treatment with good trigger management usually gives much better control.

  • What should I do if Soolantra stops working as well over time?

    If you stop seeing progress, your clinician may adjust your application routine or pair Soolantra with another medication to target different rosacea symptoms. Rosacea often changes over time, so reviewing treatment every few months can keep results stable.

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